| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2019530 | B | Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | ALA2016531 | assay format | Scientific Literature | |
| 2. | ALA2019531 | B | Inhibition of human recombinant UAE assessed as inhibition of UbcH6-Ub complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | ALA2016531 | assay format | Scientific Literature | |
| 3. | ALA2019532 | B | Inhibition of human recombinant SAE1/2 assessed as inhibition of SUMO1-UbcH9 complex formation at 0.001 to 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | ALA2016531 | protein complex format | Scientific Literature | |
| 4. | ALA2019634 | B | Inhibition of human recombinant UBA5 assessed as inhibition of UCF1-UFM1 complex formation at 10 uM after 1.5 hrs by Western blot analysis | Homo sapiens | 22 | ALA2016531 | single protein format | Scientific Literature | |
| 5. | ALA2019637 | B | Inhibition of human recombinant NAE assessed as inhibition of NEDD8-UbcH12 complex formation at 10 nM after 1.5 hrs by Western blot analysis | Homo sapiens | 7 | ALA2016531 | assay format | Scientific Literature | |
| 6. | ALA2019652 | F | Antiproliferative activity against human K562 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 17 | ALA2016531 | cell-based format | Scientific Literature | |
| 7. | ALA3880799 | B | Inhibition of recombinant human untagged NAEalpha/N-terminal His-tagged NAEbeta expressed in Bac-to-Bac expression system using FLAG-tagged NEDD8 as substrate after 90 mins in presence of GST-tagged Ubc12 by HTRF assay | Homo sapiens | 123 | ALA3880402 | assay format | Patent Bioactivity Data |
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