| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2020845 | B | Inhibition of human recombinant PDE10A assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 33 | single protein format | Scientific Literature | ||
| 2. | ALA2020846 | B | Inhibition of human recombinant PDE3A assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 19 | single protein format | Scientific Literature | ||
| 3. | ALA2020847 | B | Inhibition of human recombinant PDE7A1 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 4. | ALA2020848 | A | Clearance in human hepatocytes assessed per 10'6 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA2020849 | A | Clearance in rat hepatocytes assessed per 10'6 cells | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA2020850 | A | Clearance in monkey hepatocytes assessed per 10'6 cells | Macaca mulatta | 11 | cell-based format | Scientific Literature | ||
| 7. | ALA2020856 | P | Solubility of the compound in 2% DMSO at pH 7.4 | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA2020857 | B | Inhibition of human ERG at 10 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 9. | ALA2020858 | P | Dissociation constant, pKa of the compound | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA2020859 | B | Inhibition of human recombinant PDE1 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 5 | protein format | Scientific Literature | ||
| 11. | ALA2020860 | B | Inhibition of human recombinant PDE2 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 12. | ALA2020861 | B | Inhibition of human recombinant PDE4 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 5 | protein format | Scientific Literature | ||
| 13. | ALA2020862 | B | Inhibition of human recombinant PDE5 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 14. | ALA2020863 | B | Inhibition of human recombinant PDE6 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 5 | protein format | Scientific Literature | ||
| 15. | ALA2020864 | B | Inhibition of human recombinant PDE8 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 5 | protein format | Scientific Literature | ||
| 16. | ALA2020865 | B | Inhibition of human recombinant PDE9 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 17. | ALA2020866 | B | Inhibition of human recombinant PDE11 assessed as inhibition of [3H]cAMP hydrolysis by scintillation proximity assay | Homo sapiens | 5 | single protein format | Scientific Literature |
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