# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2019577 | B | Binding affinity to human bradykinin B1 receptor | Homo sapiens | 20 | single protein format | Scientific Literature | ||
2. | ALA2019578 | A | Intrinsic clearance in human liver microsomes assessed per gram of liver at 2.5 uM after 20 mins | Homo sapiens | 17 | microsome format | Scientific Literature | ||
3. | ALA2019579 | A | Intrinsic clearance in rat liver microsomes assessed per gram of liver at 2.5 uM after 20 mins | Rattus norvegicus | 17 | microsome format | Scientific Literature | ||
4. | ALA2019580 | F | Antagonist activity at rat bradykinin B1 receptor | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
5. | ALA2019696 | F | Antagonist activity at human bradykinin B2 receptor at 1 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
6. | ALA2019697 | F | Antiinflammatory activity in Wistar rat pain model assessed as inhibition of DABK-induced paw oedema at 0.03 mg/kg, po administered 120 mins before DABK challenge measured by plethysometric analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA2019698 | F | Antiinflammatory activity in Wistar rat pain model assessed as inhibition of DABK-induced paw oedema at 0.1 mg/kg, po administered 120 mins before DABK challenge measured by plethysometric analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA2019699 | F | Antiinflammatory activity in Wistar rat pain model assessed as inhibition of DABK-induced paw oedema at 0.3 mg/kg, po administered 120 mins before DABK challenge measured by plethysometric analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA2019703 | F | Antiinflammatory activity in po dosed Wistar rat pain model assessed as inhibition of DABK-induced paw oedema administered 120 mins before DABK challenge measured by plethysometric analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA2019704 | F | Antihyperalgesic activity in po dosed Sprague-Dawley rat assessed as decrease in CFA-induced joint pain administered 3 days post CFA challenge | Rattus norvegicus | 1 | organism-based format | Scientific Literature |