# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2019815 | B | Displacement of [3H]-cAMP from human recombinant PDE7A | Homo sapiens | 36 | single protein format | Scientific Literature | ||
2. | ALA2019816 | B | Displacement of [3H]-cAMP from human recombinant PDE7B | Homo sapiens | 3 | single protein format | Scientific Literature | ||
3. | ALA2019817 | B | Inhibition of PDE1A at 10 uM | 3 | single protein format | Scientific Literature | |||
4. | ALA2019818 | B | Inhibition of PDE2A at 10 uM | 3 | single protein format | Scientific Literature | |||
5. | ALA2019819 | B | Inhibition of PDE3A at 10 uM | 3 | single protein format | Scientific Literature | |||
6. | ALA2019820 | B | Inhibition of PDE4D at 10 uM | 3 | single protein format | Scientific Literature | |||
7. | ALA2019821 | B | Inhibition of PDE5A at 10 uM | 3 | single protein format | Scientific Literature | |||
8. | ALA2019822 | B | Inhibition of PDE8A1 at 10 uM | 3 | single protein format | Scientific Literature | |||
9. | ALA2019823 | B | Inhibition of PDE9A2 at 10 uM | 3 | single protein format | Scientific Literature | |||
10. | ALA2019824 | B | Inhibition of PDE10A at 10 uM | 3 | single protein format | Scientific Literature | |||
11. | ALA2019825 | B | Inhibition of PDE11A at 10 uM | 3 | single protein format | Scientific Literature | |||
12. | ALA2019827 | A | Metabolic stability in human liver microsomes assessed as compound remaining after 60 mins | Homo sapiens | 2 | microsome format | Scientific Literature | ||
13. | ALA2019828 | A | Metabolic stability in rat liver microsomes assessed as compound remaining after 60 mins | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
14. | ALA2019829 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining after 60 mins | Mus musculus | 2 | microsome format | Scientific Literature | ||
15. | ALA2019830 | A | Drug uptake in Sprague-Dawley rat brain at 1 mg/kg, iv measured after 5 mins | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
16. | ALA2019831 | A | Plasma concentration in Sprague-Dawley rat at 1 mg/kg, iv measured after 5 mins | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
17. | ALA2019832 | A | Ratio of drug uptake in brain to plasma of Sprague-Dawley rat at 1 mg/kg, iv measured after 5 mins | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
18. | ALA2019833 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
19. | ALA2019834 | A | AUC in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
20. | ALA2019835 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature |