# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA668109 | Binding | Dissociation rate constant of compound for mutant T46A Escherichia coli dihydrofolate reductase | Escherichia coli | 4 | ALA1125508 | single protein format | Scientific Literature | |
2. | ALA668110 | Binding | Dissociation rate constant of compound for mutant T46N Escherichia coli dihydrofolate reductase | Escherichia coli | 4 | ALA1125508 | single protein format | Scientific Literature | |
3. | ALA668111 | Binding | Dissociation rate constant of compound for mutant T46S Escherichia coli dihydrofolate reductase | Escherichia coli | 4 | ALA1125508 | single protein format | Scientific Literature | |
4. | ALA668112 | Binding | Dissociation rate constant of compound for wild type Escherichia coli dihydrofolate reductase | Escherichia coli | 4 | ALA1125508 | single protein format | Scientific Literature | |
5. | ALA667355 | Binding | Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 7 | Escherichia coli | 4 | ALA1124276 | single protein format | Scientific Literature | |
6. | ALA667979 | Binding | Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 7 | Escherichia coli | 4 | ALA1124276 | single protein format | Scientific Literature | |
7. | ALA667167 | Binding | Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | Escherichia coli | 4 | ALA1124276 | single protein format | Scientific Literature | |
8. | ALA664036 | Binding | Rate of hydride transfer (E-N) of compound for mutant T46A Escherichia coli dihydrofolate reductase; ND=no data | Escherichia coli | 1 | ALA1125508 | single protein format | Scientific Literature | |
9. | ALA664037 | Binding | Rate of hydride transfer (E-N) of compound for mutant T46N Escherichia coli dihydrofolate reductase | Escherichia coli | 1 | ALA1125508 | single protein format | Scientific Literature | |
10. | ALA664038 | Binding | Rate of hydride transfer (E-N) of compound for mutant T46S Escherichia coli dihydrofolate reductase; ND=no data | Escherichia coli | 1 | ALA1125508 | single protein format | Scientific Literature | |
11. | ALA667939 | Binding | Rate of hydride transfer (E-N) of compound for wild type Escherichia coli dihydrofolate reductase | Escherichia coli | 1 | ALA1125508 | single protein format | Scientific Literature | |
12. | ALA667940 | Binding | Rate of hydride transfer (E-NH) of compound for mutant T46A Escherichia coli dihydrofolate reductase | Escherichia coli | 1 | ALA1125508 | single protein format | Scientific Literature | |
13. | ALA667941 | Binding | Rate of hydride transfer (E-NH) of compound for mutant T46N Escherichia coli dihydrofolate reductase | Escherichia coli | 1 | ALA1125508 | single protein format | Scientific Literature | |
14. | ALA667942 | Binding | Rate of hydride transfer (E-NH) of compound for mutant T46S Escherichia coli dihydrofolate reductase | Escherichia coli | 1 | ALA1125508 | single protein format | Scientific Literature | |
15. | ALA667943 | Binding | Rate of hydride transfer (E-NH) of compound for wild type Escherichia coli dihydrofolate reductase | Escherichia coli | 1 | ALA1125508 | single protein format | Scientific Literature | |
16. | ALA677067 | Binding | Activity (apparent Km ) was evaluated in vitro by purified mouse liver folate polyglutamate synthetase (FPGS). | 6 | ALA1122902 | assay format | Scientific Literature | ||
17. | ALA678779 | Binding | Activity (relative Km ) was evaluated in vitro by purified mouse liver folate polyglutamate synthetase (FPGS). | 5 | ALA1122902 | assay format | Scientific Literature | ||
18. | ALA678781 | Binding | Activity (relative Vmax) was evaluated in vitro by purified mouse liver folate polyglutamate synthetase (FPGS). | 6 | ALA1122902 | assay format | Scientific Literature | ||
19. | ALA678794 | Binding | Apparent kinetic constant of substrate activity for Hog liver Folyl-polyglutamate synthase | Sus scrofa | 9 | ALA1125864 | assay format | Scientific Literature | |
20. | ALA678885 | Binding | Relative maximum velocity of substrate activity for Hog liver Folyl-polyglutamate synthase (relative to control of 50 uM aminopterin) | Sus scrofa | 8 | ALA1125864 | assay format | Scientific Literature |