| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1034553 | B | Inhibition of HIF1 by luciferase reporter gene assay | 1 | assay format | Scientific Literature | |||
| 2. | ALA1034554 | F | Inhibition of hopoxia-induced HIF1alpha expression in mouse 4T1 cells at 100 nM after 24 hrs by Western blotting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA1034555 | F | Inhibition of CoCl2-induced HIF1alpha expression in mouse 4T1 cells at 100 nM after 24 by Western blotting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1034556 | F | Inhibition of 1,10-phenanthroline-induced HIF1alpha expression in human T47D cells after 16 hrs by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1034557 | F | Inhibition of CoCl2-induced HIF1alpha expression in human MDA-MB-231 cells after 24 hrs by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1034558 | F | Inhibition of hypoxia-induced VEGF secretion in mouse 4T1 cells at 100 nM after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1034559 | F | Inhibition of hypoxia-induced VEGF secretion in mouse 4T1 cells at 1 uM after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA1034560 | A | Cytotoxicity against mouse 4T1 cells assessed as cell survival up to 10 uM after 24 hrs by MTS assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1034561 | A | Therapeutic index, ratio of IC50 for mouse 4T1 cells to IC50 for HIF1 | 1 | cell-based format | Scientific Literature | |||
| 10. | ALA1034562 | F | Inhibition of hopoxia-induced HIF1alpha expression in mouse 4T1 cells at 1 uM after 24 hrs by Western blotting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2327237 | B | Inhibition of hypoxia-induced HIF1 transcriptional activity in human T47D cells by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3106980 | U | Selectivity index, ratio of CC50 for human P3HR1 cells to EC50 for EBV infected in human P3HR1 cells | 28 | cell-based format | Scientific Literature | |||
| 13. | ALA3106981 | A | Cytotoxicity against human P3HR1 cells assessed as cell viability after 2 days by trypan blue staining-based light microscopy | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 14. | ALA3106982 | F | Antiviral activity against EBV infected in human P3HR1 cells assessed as inhibition of lytic viral DNA replication after 48 hrs by RT-PCR analysis | Human gammaherpesvirus 4 | 28 | organism-based format | Scientific Literature | ||
| 15. | ALA3223404 | B | Inhibition of HIF-1 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA3625031 | F | Cytotoxicity against human breast cancer cells by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3625032 | F | Cytotoxicity against human leukemia cells by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3625033 | F | Cytotoxicity against human melanoma cells by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA3625034 | A | Cytotoxicity against human HEK293T cells assessed as survival rate at 10 uM after 24 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 20. | ALA3625035 | B | Inhibition of HIF1 in human HEK293T cells transfected with pGL3-5HRE-VEGF and pRL-SV40 after 24 hrs by dual luciferase reporter assay | Homo sapiens | 13 | cell-based format | Scientific Literature |
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