# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2026216 | B | Inhibition of GPIbalpha-human vWF binding assessed as platelet rolling velocity at 100 uM preincubated for 5 mins by parallel plate flow assay with real time imaging microscopy (Rvb = 7.1 um/sec) | Homo sapiens | 3 | assay format | Scientific Literature | ||
2. | ALA2026550 | B | Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay using washed platelets from male (Rvb = 58%) | 3 | assay format | Scientific Literature | |||
3. | ALA2026551 | B | Inhibition of GPIbalpha-vWF binding assessed as ristocetin-induced platelet agglutination at 100 uM after 2 mins by static agglutination assay using washed platelets from female (Rvb = 61.7%) | 3 | assay format | Scientific Literature | |||
4. | ALA2026554 | B | Inhibition of GPIbalpha-vWF binding assessed as constant shear stress at 120 dynes/cm'2-induced platelet agglutination at 10 uM preincubated for 5 mins by cone and plate rheometer analysis relative to control using male platelet rich plasma (Rvb = 100%) | 2 | cell-free format | Scientific Literature | |||
5. | ALA2026555 | B | Inhibition of GPIbalpha-vWF binding assessed as constant shear stress at 120 dynes/cm'2-induced platelet agglutination at 10 uM preincubated for 5 mins by cone and plate rheometer analysis relative to control using female platelet rich plasma (Rvb = 100%) | 2 | cell-free format | Scientific Literature |