# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2026306 | F | Trypanocidal activity against bloodstream form of Trypanosoma cruzi Y isolated from albino mouse blood after 24 hrs by neubauer chamber analysis | Trypanosoma cruzi | 35 | ALA2021832 | organism-based format | Scientific Literature | |
2. | ALA2026307 | F | Ratio of benznidazole IC50 to compound IC50 for bloodstream form of Trypanosoma cruzi Y | Trypanosoma cruzi | 6 | ALA2021832 | organism-based format | Scientific Literature | |
3. | ALA2026309 | A | Cytotoxicity against mouse embryo HMC after 24 hrs by Alamar blue assay | Mus musculus | 4 | ALA2021832 | assay format | Scientific Literature | |
4. | ALA2026310 | U | Selectivity index, ratio of LC50 for mouse embryo HMC to IC50 for bloodstream form of Trypanosoma cruzi Y | 4 | ALA2021832 | assay format | Scientific Literature | ||
5. | ALA2378251 | F | Ratio of potassium antimonyl tartrate IC50 to compound IC50 for antimony-sensitive Leishmania amazonensis MHOM/BR/1989/BA199 promastigote infected in Swiss mouse peritoneal macrophages | Leishmania amazonensis | 12 | ALA2375264 | organism-based format | Scientific Literature | |
6. | ALA2378252 | F | Ratio of potassium antimonyl tartrate IC50 to compound IC50 for antimony-sensitive Leishmania infantum MCAN/BR/2002/BH400 promastigote infected in Swiss mouse peritoneal macrophages | Leishmania infantum | 12 | ALA2375264 | organism-based format | Scientific Literature | |
7. | ALA2378253 | F | Selectivity index, ratio of CC50 for Swiss mouse peritoneal macrophages to IC50 for antimony-resistant Leishmania amazonensis MHOM/BR/1989/BA199 promastigote | 28 | ALA2375264 | assay format | Scientific Literature | ||
8. | ALA2378254 | F | Selectivity index, ratio of CC50 for Swiss mouse peritoneal macrophages to IC50 for antimony-sensitive Leishmania amazonensis MHOM/BR/1989/BA199 promastigote | 28 | ALA2375264 | assay format | Scientific Literature | ||
9. | ALA2378255 | F | Selectivity index, ratio of CC50 for Swiss mouse peritoneal macrophages to IC50 for antimony-resistant Leishmania infantum MCAN/BR/2002/BH400 promastigote | 28 | ALA2375264 | assay format | Scientific Literature | ||
10. | ALA2378256 | F | Selectivity index, ratio of CC50 for Swiss mouse peritoneal macrophages to IC50 for antimony-sensitive Leishmania infantum MCAN/BR/2002/BH400 promastigote | 28 | ALA2375264 | assay format | Scientific Literature | ||
11. | ALA2378257 | A | Cytotoxicity against Swiss mouse peritoneal macrophages after 24 hrs by MTT assay | Mus musculus | 28 | ALA2375264 | cell-based format | Scientific Literature | |
12. | ALA2378258 | F | Antileishmanial activity against antimony-resistant Leishmania amazonensis MHOM/BR/1989/BA199 promastigote infected in Swiss mouse peritoneal macrophages after 72 hrs | Leishmania amazonensis | 28 | ALA2375264 | organism-based format | Scientific Literature | |
13. | ALA2378259 | F | Antileishmanial activity against antimony-sensitive Leishmania amazonensis MHOM/BR/1989/BA199 promastigote infected in Swiss mouse peritoneal macrophages after 72 hrs | Leishmania amazonensis | 28 | ALA2375264 | organism-based format | Scientific Literature | |
14. | ALA2378260 | F | Antileishmanial activity against antimony-resistant Leishmania infantum MCAN/BR/2002/BH400 promastigote infected in Swiss mouse peritoneal macrophages after 72 hrs | Leishmania infantum | 28 | ALA2375264 | organism-based format | Scientific Literature | |
15. | ALA2378261 | F | Antileishmanial activity against antimony-sensitive Leishmania infantum MCAN/BR/2002/BH400 promastigote infected in Swiss mouse peritoneal macrophages after 72 hrs | Leishmania infantum | 28 | ALA2375264 | organism-based format | Scientific Literature | |
16. | ALA4343211 | F | Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 17 | ALA4342418 | cell-based format | Scientific Literature | |
17. | ALA4343310 | A | Cytotoxicity against human PBMC cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 4 | ALA4342418 | cell-based format | Scientific Literature | |
18. | ALA4343321 | F | Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 2 | ALA4342418 | cell-based format | Scientific Literature | |
19. | ALA4343322 | F | Antiproliferative activity against human K562-Lucena 1 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 2 | ALA4342418 | cell-based format | Scientific Literature |