# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2026306 | Functional | Trypanocidal activity against bloodstream form of Trypanosoma cruzi Y isolated from albino mouse blood after 24 hrs by neubauer chamber analysis | Trypanosoma cruzi | 35 | ALA2021832 | organism-based format | Scientific Literature | |
2. | ALA4390969 | Binding | Inhibition of Schistosoma mansoni DHODH assessed as remaining enzyme activity at 500 uM using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assay relative to control | Schistosoma mansoni | 15 | ALA4390643 | single protein format | Scientific Literature | |
3. | ALA4390974 | Binding | Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assay | Schistosoma mansoni | 28 | ALA4390643 | single protein format | Scientific Literature | |
4. | ALA4390975 | ADME | Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assay | Homo sapiens | 28 | ALA4390643 | single protein format | Scientific Literature | |
5. | ALA4390981 | Toxicity | Selectivity Index, ratio of IC50 for Schistosoma mansoni DHODH to IC50 for human DHODH to IC50 | 5 | ALA4390643 | assay format | Scientific Literature |