# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2025125 | B | Inhibition of Pseudomonas aeruginosa LpxC expressed in Escherichia coli using UDP-3-O-N-acetylglucosamine substrate measured after 30 mins by mass spectrometry | Pseudomonas aeruginosa | 50 | assay format | Scientific Literature | ||
2. | ALA2025126 | F | Antimicrobial activity against Pseudomonas aeruginosa PA3919 with (delta(mexAB-OprM)delta(mexXY)delta(MexZ) phenotype after 16 to 20 hrs by 2-fold microbroth dilution method | Pseudomonas aeruginosa | 50 | organism-based format | Scientific Literature | ||
3. | ALA2025127 | F | Antimicrobial activity against wild type Pseudomonas aeruginosa PA01 after 16 to 20 hrs by 2-fold microbroth dilution method | Pseudomonas aeruginosa | 50 | organism-based format | Scientific Literature | ||
4. | ALA2025128 | P | Thermodynamic solubility of the compound in thermosol at pH 3.0 | 4 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA2025129 | P | Thermodynamic solubility of the compound in thermosol at pH 7.4 | 4 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA2025130 | P | Thermodynamic solubility of the compound in thermosol at pH 9 | 4 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA2025131 | A | Fraction unbound in rat plasma relative to untreated control | Rattus norvegicus | 4 | cell-free format | Scientific Literature | ||
8. | ALA2025132 | A | Fraction unbound in human plasma relative to untreated control | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
9. | ALA2025133 | A | Clearance in rat at 10 mg/kg | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
10. | ALA2025134 | A | Volume of distribution at steady state in rat at 10 mg/kg | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
11. | ALA2025135 | A | Half life in rat at 10 mg/kg | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
12. | ALA2025136 | A | AUC in rat at 10 mg/kg | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
13. | ALA2025137 | A | Free AUC in rat at 10 mg/kg | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
14. | ALA2025138 | F | Antimicrobial activity against Pseudomonas aeruginosa after 16 to 20 hrs by 2-fold microbroth dilution method | Pseudomonas aeruginosa | 14 | organism-based format | Scientific Literature | ||
15. | ALA2025139 | F | Antimicrobial activity against Escherichia coli after 16 to 20 hrs by 2-fold microbroth dilution method | Escherichia coli | 14 | organism-based format | Scientific Literature | ||
16. | ALA2025140 | F | Antimicrobial activity against Klebsiella pneumoniae after 16 to 20 hrs by 2-fold microbroth dilution method | Klebsiella pneumoniae | 14 | organism-based format | Scientific Literature | ||
17. | ALA2025141 | F | Antimicrobial activity against Acinetobacter sp. after 16 to 20 hrs by 2-fold microbroth dilution method | Acinetobacter sp. | 14 | organism-based format | Scientific Literature | ||
18. | ALA2025142 | F | Antimicrobial activity against Enterobacter aerogenes after 16 to 20 hrs by 2-fold microbroth dilution method | Klebsiella aerogenes | 14 | organism-based format | Scientific Literature | ||
19. | ALA2025277 | F | Antimicrobial activity against Citrobacter freundii after 16 to 20 hrs by 2-fold microbroth dilution method | Citrobacter freundii | 14 | organism-based format | Scientific Literature |