| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2025296 | F | Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization by FLIPR analysis | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 2. | ALA2025297 | F | Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization by FLIPR analysis relative to PHCCC | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 3. | ALA2025298 | F | Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as fold shift in calcium mobilization by FLIPR analysis relative to glutamate | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA2025321 | A | Inhibition of CYP3A4 at 5 uM | 3 | single protein format | Scientific Literature | |||
| 5. | ALA2025322 | A | Inhibition of CYP2C9 at 5 uM | 2 | single protein format | Scientific Literature | |||
| 6. | ALA2025323 | A | Inhibition of CYP2B6 at 5 uM | 3 | single protein format | Scientific Literature | |||
| 7. | ALA2025324 | P | Kinetic solubility of the compound at pH 7.4 | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA2025325 | P | Kinetic solubility of the compound at pH 4.0 | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA2025326 | A | Plasma protein binding in rat | Rattus norvegicus | 3 | cell-free format | Scientific Literature | ||
| 10. | ALA2025327 | A | Fraction unbound in rat brain | Rattus norvegicus | 3 | tissue-based format | Scientific Literature | ||
| 11. | ALA2025332 | A | Intrinsic clearance in human | Homo sapiens | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA2025333 | A | Intrinsic clearance in rat | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA2025500 | A | Inhibition of CYP2C19 at 5 uM | 1 | single protein format | Scientific Literature | |||
| 14. | ALA2025501 | A | Drug uptake in rat brain at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA2025502 | A | Plasma concentration in rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA2025503 | A | Drug uptake in rat CSF at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA2025504 | A | Ratio of drug level in brain to plasma in rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature |
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