| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2025934 | B | Inhibition of human CA1 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 2. | ALA2027661 | B | Inhibition of human CA2 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 3. | ALA2027662 | B | Inhibition of human CA9 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 4. | ALA2027663 | B | Inhibition of human CA12 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 28 | single protein format | Scientific Literature | ||
| 5. | ALA2341293 | B | Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-2 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydration stopped-flow assay | Drosophila melanogaster | 28 | assay format | Scientific Literature | ||
| 6. | ALA2341294 | B | Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydration stopped-flow assay | Drosophila melanogaster | 28 | assay format | Scientific Literature | ||
| 7. | ALA4268729 | B | Inhibition of Escherichia coli NDM4 assessed as potentiation of meropenem-induced antibacterial activity by measuring zone of inhibition at 10 uL after 16 to 18 hrs by disc diffusion method (Rvb = 9.6 +/- 0.5 millimeter) | Escherichia coli | 9 | single protein format | Scientific Literature | ||
| 8. | ALA4268730 | B | Inhibition of Escherichia coli IMP4 assessed as potentiation of meropenem-induced antibacterial activity by measuring zone of inhibition at 10 uL after 16 to 18 hrs by disc diffusion method (Rvb = 9.8 +/- 0.6 millimeter) | Escherichia coli | 9 | assay format | Scientific Literature | ||
| 9. | ALA4268736 | B | Inhibition of Escherichia coli NDM1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 10 to 320 ug/ml) | Escherichia coli | 9 | single protein format | Scientific Literature | ||
| 10. | ALA4268737 | B | Inhibition of Proteus mirabilis NDM1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 20 to 160 ug/ml) | Proteus mirabilis | 9 | assay format | Scientific Literature | ||
| 11. | ALA4268738 | B | Inhibition of Citrobacter freundii NDM1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 20 ug/ml) | Citrobacter freundii | 7 | assay format | Scientific Literature | ||
| 12. | ALA4268739 | B | Inhibition of Klebsiella pneumoniae NDM1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 40 to 80 ug/ml) | Klebsiella pneumoniae | 9 | single protein format | Scientific Literature | ||
| 13. | ALA4268740 | B | Inhibition of Klebsiella pneumoniae IMP4 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 20 to 40 ug/ml) | Klebsiella pneumoniae | 9 | single protein format | Scientific Literature | ||
| 14. | ALA4268741 | B | Inhibition of Escherichia coli IMP4 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 20 to 160 ug/ml) | Escherichia coli | 9 | assay format | Scientific Literature |
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