# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2025934 | B | Inhibition of human CA1 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 28 | ALA2021877 | single protein format | Scientific Literature | |
2. | ALA2027661 | B | Inhibition of human CA2 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 28 | ALA2021877 | single protein format | Scientific Literature | |
3. | ALA2027662 | B | Inhibition of human CA9 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 28 | ALA2021877 | single protein format | Scientific Literature | |
4. | ALA2027663 | B | Inhibition of human CA12 pre-incubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 28 | ALA2021877 | single protein format | Scientific Literature | |
5. | ALA2027665 | F | Antiglaucoma activity in carbomer-induced glaucoma in albino rabbit assessed as reduction in intra ocular pressure dosed as 2% compound solution measured 3 to 4 hrs post dose | Oryctolagus cuniculus | 2 | ALA2021877 | organism-based format | Scientific Literature | |
6. | ALA2027666 | F | Antiglaucoma activity in carbomer-induced glaucoma in albino rabbit assessed as reduction in intra ocular pressure dosed as 2% compound solution measured 2 hrs post dose (vehicle treated contralateral eye Rvb = 37 to 40 mmHg) | Oryctolagus cuniculus | 1 | ALA2021877 | organism-based format | Scientific Literature | |
7. | ALA2027667 | F | Antiglaucoma activity in carbomer-induced glaucoma in albino rabbit assessed as reduction in intra ocular pressure dosed as 2% compound solution | Oryctolagus cuniculus | 2 | ALA2021877 | organism-based format | Scientific Literature | |
8. | ALA2341293 | B | Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-2 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydration stopped-flow assay | Drosophila melanogaster | 28 | ALA2331089 | assay format | Scientific Literature | |
9. | ALA2341294 | B | Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydration stopped-flow assay | Drosophila melanogaster | 28 | ALA2331089 | assay format | Scientific Literature | |
10. | ALA4268736 | B | Inhibition of Escherichia coli NDM1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 10 to 320 ug/ml) | Escherichia coli | 9 | ALA4265960 | single protein format | Scientific Literature | |
11. | ALA4268737 | B | Inhibition of Proteus mirabilis NDM1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 20 to 160 ug/ml) | Proteus mirabilis | 9 | ALA4265960 | assay format | Scientific Literature | |
12. | ALA4268738 | B | Inhibition of Citrobacter freundii NDM1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 20 ug/ml) | Citrobacter freundii | 7 | ALA4265960 | assay format | Scientific Literature | |
13. | ALA4268739 | B | Inhibition of Klebsiella pneumoniae NDM1 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 40 to 80 ug/ml) | Klebsiella pneumoniae | 9 | ALA4265960 | single protein format | Scientific Literature | |
14. | ALA4268740 | B | Inhibition of Klebsiella pneumoniae IMP4 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 20 to 40 ug/ml) | Klebsiella pneumoniae | 9 | ALA4265960 | single protein format | Scientific Literature | |
15. | ALA4268741 | B | Inhibition of Escherichia coli IMP4 assessed as potentiation of meropenem-induced antibacterial activity by measuring meropenem MIC at 64 ug/ml after 16 to 18 hrs by broth microdilution method (Rvb = 20 to 160 ug/ml) | Escherichia coli | 9 | ALA4265960 | assay format | Scientific Literature |