# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2025841 | B | Displacement of fluorescein-labeled phosphotyrosine-peptide derived from the interleukin-6 receptor subunit gp130 from the STAT3 after 15 mins by fluorescent polarization assay | 10 | ALA2021835 | single protein format | Scientific Literature | ||
2. | ALA2025842 | B | Displacement of 5-carboxyfluorescein-labeled GpYLVLDKW from the STAT5b-SH2 domain after 15 mins by fluorescent polarization assay | 10 | ALA2021835 | single protein format | Scientific Literature | ||
3. | ALA2025843 | B | Displacement of radioligand from the STAT1 after 15 mins by fluorescent polarization assay | 10 | ALA2021835 | single protein format | Scientific Literature | ||
4. | ALA2025847 | F | Cytotoxicity against human MV4-11 cells expressing STAT5 after 48 hrs by alamar blue fluorescent staining | Homo sapiens | 5 | ALA2021835 | cell-based format | Scientific Literature | |
5. | ALA2025848 | F | Cytotoxicity against human K562 cells expressing STAT5 after 48 hrs by alamar blue fluorescent staining | Homo sapiens | 5 | ALA2021835 | cell-based format | Scientific Literature | |
6. | ALA2025945 | B | Inhibition of STAT5-mediated MCL-1 expression in human K562 cells at 40 uM after 6 hrs by RT-PCR analysis | Homo sapiens | 4 | ALA2021835 | cell-based format | Scientific Literature | |
7. | ALA2025946 | B | Inhibition of STAT5-mediated C-MYC expression in human K562 cells at 40 uM after 6 hrs by RT-PCR analysis | Homo sapiens | 4 | ALA2021835 | cell-based format | Scientific Literature | |
8. | ALA2025947 | B | Inhibition of STAT5-mediated cyclin D1 expression in human K562 cells at 40 uM after 6 hrs by RT-PCR analysis | Homo sapiens | 4 | ALA2021835 | cell-based format | Scientific Literature | |
9. | ALA2025948 | B | Inhibition of STAT5-mediated cyclin D2 expression in human K562 cells at 40 uM after 6 hrs by RT-PCR analysis | Homo sapiens | 4 | ALA2021835 | cell-based format | Scientific Literature | |
10. | ALA3226171 | B | Inhibition of papaya papain assessed as Z-Phe-Arg-pNA hydrolysis by fluorometric kinetic-based assay | Carica papaya | 6 | ALA3217656 | single protein format | Scientific Literature | |
11. | ALA3226172 | B | Inhibition of human GST-tagged full length MKPX assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
12. | ALA3226173 | B | Inhibition of human GST-tagged PRL2 A/S active mutant assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | assay format | Scientific Literature | |
13. | ALA3226174 | B | Inhibition of human GST-tagged TC-PTP catalytic domain assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
14. | ALA3226175 | B | Inhibition of human GST-tagged PTP-sigma D1D2 domain assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
15. | ALA3226176 | B | Inhibition of human GST-tagged PTP1B catalytic domain assessed as DiFMUP hydrolysis by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
16. | ALA3226177 | B | Inhibition of papaya papain assessed as Z-Phe-Arg-pNA hydrolysis at 10 uM by fluorometric kinetic-based assay | Carica papaya | 6 | ALA3217656 | single protein format | Scientific Literature | |
17. | ALA3226178 | B | Inhibition of human GST-tagged full length MKPX assessed as DiFMUP hydrolysis at 10 uM by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
18. | ALA3226179 | B | Inhibition of human GST-tagged PRL2 A/S active mutant assessed as DiFMUP hydrolysis at 10 uM by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | assay format | Scientific Literature | |
19. | ALA3226180 | B | Inhibition of human GST-tagged PTP-LAR D1D2 domain assessed as DiFMUP hydrolysis at 10 uM by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature | |
20. | ALA3226181 | B | Inhibition of human GST-tagged PTP-sigma D1D2 domain assessed as DiFMUP hydrolysis at 10 uM by fluorometric kinetic-based assay | Homo sapiens | 6 | ALA3217656 | single protein format | Scientific Literature |