# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2025841 | B | Displacement of fluorescein-labeled phosphotyrosine-peptide derived from the interleukin-6 receptor subunit gp130 from the STAT3 after 15 mins by fluorescent polarization assay | 10 | single protein format | Scientific Literature | |||
2. | ALA2025842 | B | Displacement of 5-carboxyfluorescein-labeled GpYLVLDKW from the STAT5b-SH2 domain after 15 mins by fluorescent polarization assay | 10 | single protein format | Scientific Literature | |||
3. | ALA2025843 | B | Displacement of radioligand from the STAT1 after 15 mins by fluorescent polarization assay | 10 | single protein format | Scientific Literature | |||
4. | ALA2025844 | B | Selectivity ratio of Ki for STAT1 to Ki for STAT5b-SH2 domain | 6 | assay format | Scientific Literature | |||
5. | ALA2025845 | B | Selectivity ratio of Ki for STAT3 to Ki for STAT5b-SH2 domain | 6 | assay format | Scientific Literature | |||
6. | ALA2025847 | F | Cytotoxicity against human MV4-11 cells expressing STAT5 after 48 hrs by alamar blue fluorescent staining | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA2025848 | F | Cytotoxicity against human K562 cells expressing STAT5 after 48 hrs by alamar blue fluorescent staining | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA2025854 | B | Inhibition of BCR-ABL-mediated STAT5 phosphorylation in human K562 cells after 6 hrs by Western blotting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA2025945 | B | Inhibition of STAT5-mediated MCL-1 expression in human K562 cells at 40 uM after 6 hrs by RT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA2025946 | B | Inhibition of STAT5-mediated C-MYC expression in human K562 cells at 40 uM after 6 hrs by RT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA2025947 | B | Inhibition of STAT5-mediated cyclin D1 expression in human K562 cells at 40 uM after 6 hrs by RT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
12. | ALA2025948 | B | Inhibition of STAT5-mediated cyclin D2 expression in human K562 cells at 40 uM after 6 hrs by RT-PCR analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA2434703 | B | Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after 30 mins by fluorescence polarization assay | Homo sapiens | 75 | single protein format | Scientific Literature | ||
14. | ALA2434704 | B | Binding affinity to Stat3 (unknown origin) using hSIE as probe preincubated for 30 mins followed by hSIE addition by electrophoretic mobility shift assay | Homo sapiens | 8 | single protein format | Scientific Literature |