# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2025951 | B | Displacement of [3H] epibatidine from rat alpha2beta2 nAChR by beta scintillation counting | Rattus norvegicus | 10 | protein complex format | Scientific Literature | ||
2. | ALA2025952 | B | Displacement of [3H] epibatidine from rat alpha2beta4 nAChR by beta scintillation counting | Rattus norvegicus | 10 | protein complex format | Scientific Literature | ||
3. | ALA2025953 | B | Displacement of [3H] epibatidine from rat alpha3beta2 nAChR by beta scintillation counting | Rattus norvegicus | 10 | protein complex format | Scientific Literature | ||
4. | ALA2025954 | B | Displacement of [3H] epibatidine from rat alpha3beta4 nAChR by beta scintillation counting | Rattus norvegicus | 10 | protein complex format | Scientific Literature | ||
5. | ALA2025955 | B | Displacement of [3H] epibatidine from rat alpha4beta2 nAChR by beta scintillation counting | Rattus norvegicus | 10 | protein complex format | Scientific Literature | ||
6. | ALA2025956 | B | Displacement of [3H] epibatidine from rat alpha4beta2* nAChR in rat forebrain by beta scintillation counting | Rattus norvegicus | 10 | assay format | Scientific Literature | ||
7. | ALA2025957 | B | Displacement of [3H] epibatidine from rat alpha4beta4 nAChR by beta scintillation counting | Rattus norvegicus | 10 | protein complex format | Scientific Literature | ||
8. | ALA2025958 | B | Selectivity ratio of Ki for rat alpha3beta4 to Ki for rat alpha4beta2 | Rattus norvegicus | 11 | assay format | Scientific Literature | ||
9. | ALA2025963 | F | Agonist activity at human alpha4beta2 nAChR expressed in SH-EP1 cells assessed as 86Rb+ ion efflux after 9.5 mins by flip-plate technique | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
10. | ALA2025964 | F | Agonist activity at human high sensitive and low sensitive alpha4beta2 nAChR expressed in SH-EP1 cells assessed as 86Rb+ ion efflux by flip-plate technique relative to sazetidine-A | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
11. | ALA2025965 | F | Partial agonist activity at human high sensitive alpha4beta2 nAChR expressed in SH-EP1 cells assessed as 86Rb+ ion efflux by flip-plate technique relative to sazetidine-A | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
12. | ALA2025966 | F | Antagonist activity at human alpha4beta2 nAChR expressed in SH-EP1 cells assessed as inhibition of carbamylcholine induced 86Rb+ ion efflux preincubated for 10 mins prior to carbamylcholine-induction measured after 5 mins by flip-plate technique | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
13. | ALA2025967 | F | Antagonist activity at human high sensitive and low sensitive alpha4beta2 nAChR expressed in SH-EP1 cells assessed as inhibition of carbamylcholine induced 86Rb+ ion efflux preincubated for 10 mins prior to carbamylcholine-induction measured after 5 mins by flip-plate technique relative to control | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
14. | ALA2025968 | F | Agonist activity at human alpha1beta1gammadelta nAChR expressed in TE671/RD cells at 10 uM by 86Rb+ flux assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
15. | ALA2025969 | F | Antagonist activity at human alpha1beta1gammadelta nAChR expressed in TE671/RD cells at 10 uM by 86Rb+ flux assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
16. | ALA2025970 | F | Agonist activity at alpha3beta4alpha5beta2 in human SH-SY5Y cells at 10 uM by 86Rb+ flux assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
17. | ALA2025971 | F | Antagonist activity at alpha3beta4alpha5beta2 in human SH-SY5Y cells at 10 uM by 86Rb+ flux assay | Homo sapiens | 11 | cell-based format | Scientific Literature |