| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2026217 | F | Effect on sphingolipidome in human A549 cells assessed as increase in total ceramides at 10 uM after 24 hrs by UPLC-TOF analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA2026219 | F | Effect on sphingolipidome in human A549 cells assessed as increase in dihydroceramide per 10'6 cells at 10 uM after 24 hrs by UPLC-TOF analysis relative to control (Rvb = 6.5 +/- 0.42 pmol/10'6 cells) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA2026233 | F | Cytotoxicity against human A549 cells after 24 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA2026234 | F | Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA2026240 | B | Inhibition of Des1 in human A549 cells assessed as formation of CerC6NBD from dhCerC6NBD at =>100 uM after 4 hrs by HPLC-FD analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA2026241 | B | Inhibition of Des1 in human HCT116 cells assessed as formation of CerC6NBD from dhCerC6NBD at =>100 uM after 4 hrs by HPLC-FD analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA2026243 | B | Inhibition of aSMase expressed in human A549 cells using 6-hexadecanoylamino-4-methylumbelliferylphosphorylcholine as substrate at 40 uM after 2 hrs by spectrophotometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2026245 | B | Inhibition of glucocerebrosidase in human A549 cells using 4-methylumbelliferyl beta-D-glucoside as substrate at 40 uM after 45 mins by spectrophotometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2026159 | B | Inhibition of aCDase in Moh.pAS AcCer10X cells using RBM14C12 as substrate after 1 hr by HPLC-FD analysis | 3 | cell-based format | Scientific Literature | |||
| 10. | ALA2026160 | B | Inhibition of aCDase using RBM14C12 as substrate after 1 hr by HPLC-FD analysis | 3 | single protein format | Scientific Literature | |||
| 11. | ALA2026161 | B | Inhibition of nCDase in Moh.pAS cells using CerC12NBD as substrate after 1 hr by HPLC-FD analysis | 3 | cell-based format | Scientific Literature | |||
| 12. | ALA2026162 | B | Inhibition of nCDase using CerC12NBD as substrate after 1 hr by HPLC-FD analysis | 3 | single protein format | Scientific Literature | |||
| 13. | ALA2026166 | B | Inhibition of human aSMase using 6-hexadecanoylamino-4-methylumbelliferylphosphorylcholine as substrate at 100 uM preincubated for 30 mins prior substrate addition measured after 2 hrs by spectrophotometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA2026168 | B | Inhibition of human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucoside as substrate at 100 uM preincubated prior substrate addition measured after 45 mins by spectrophotometry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA2026169 | B | Inhibition of SM synthase in human A549 cells using CerC6NBD as substrate preincubated for 24 hrs prior substrate addition measured after 3 hrs by HPLC-FD analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA2026170 | B | Inhibition of GlcCer synthase in human A549 cells using CerC6NBD as substrate preincubated for 24 hrs prior substrate addition measured after 3 hrs by HPLC-FD analysis | Homo sapiens | 3 | cell-based format | Scientific Literature |
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