| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2026217 | F | Effect on sphingolipidome in human A549 cells assessed as increase in total ceramides at 10 uM after 24 hrs by UPLC-TOF analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA2026218 | F | Effect on sphingolipidome in human A549 cells assessed as increase in C18-ceramide per 10'6 cells at 10 uM after 24 hrs by UPLC-TOF analysis (Rvb = 4.8 +/- 0.5 pmol/10'6 cells) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA2026219 | F | Effect on sphingolipidome in human A549 cells assessed as increase in dihydroceramide per 10'6 cells at 10 uM after 24 hrs by UPLC-TOF analysis relative to control (Rvb = 6.5 +/- 0.42 pmol/10'6 cells) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA2026220 | F | Effect on sphingolipidome in human HCT116 cells assessed as increase in dihydroceramide per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA2026221 | F | Effect on sphingolipidome in human HCT116 cells assessed as increase in dihydrosphingomyelins per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA2026222 | F | Effect on sphingolipidome in human HCT116 cells assessed as increase in glucosyldihydroceramides per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA2026223 | F | Effect on sphingolipidome in human HCT116 cells assessed as reduction in glucosylceramides per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA2026224 | F | Effect on sphingolipidome in human HCT116 cells assessed as reduction in sphingomyelins per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA2026225 | F | Effect on sphingolipidome in human HCT116 cells assessed as increase in total ceramides per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA2026226 | F | Effect on sphingolipidome in human HCT116 cells assessed as increase in C18-ceramide per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control (Rvb = 3.9 +/- 0.3 pmol/10'6 cells) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA2026227 | F | Effect on sphingolipidome in human HCT116 cells assessed as reduction in C24-ceramide per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA2026228 | F | Effect on sphingolipidome in human HCT116 cells assessed as reduction in C16-sphingomyelin per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA2026229 | F | Effect on sphingolipidome in human HCT116 cells assessed as sphingosine-1-phosphate level per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis (Rvb = 1.49 +/- 0.70/10'6 cells) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA2026230 | F | Effect on sphingolipidome in human HCT116 cells assessed as dihydrosphingosine-1-phosphate level per 10'6 cells at 10 uM after 14 hrs by UPLC-TOF analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA2026231 | A | Drug metabolism in human A549 cells assessed as conversion to C1-O-phosphocholine derivative by UPLC-TOF analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA2026232 | A | Drug metabolism in human HCT116 cells assessed as conversion to C1-O-phosphocholine derivative by UPLC-TOF analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA2026233 | F | Cytotoxicity against human A549 cells after 24 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA2026234 | F | Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA2026235 | F | Induction of apoptosis in human HCT116 cells at 15 uM after 14 hrs by Annexin V-propidium iodide staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA2026237 | F | Induction of cell cycle arrest in human HCT116 cells at 20 uM after 14 hrs by Annexin V-propidium iodide staining based flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature |
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