| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2094261 | F | MMV: Screen against Mtb, single point, non replicating, at 25uM | Mycobacterium tuberculosis | 399 | organism-based format | MMV Malaria Box | ||
| 2. | ALA2094262 | F | MMV: Screen against Mtb, single point, replicating, at 25uM | Mycobacterium tuberculosis | 399 | organism-based format | MMV Malaria Box | ||
| 3. | ALA2094263 | F | MMV: CRC and MIC90 against Mtb (non replicating) | Mycobacterium tuberculosis | 55 | organism-based format | MMV Malaria Box | ||
| 4. | ALA2094264 | F | MMV: CRC and MIC90 against Mtb (replicating) | Mycobacterium tuberculosis | 56 | organism-based format | MMV Malaria Box | ||
| 5. | ALA2094265 | T | MMV: Cytotoxicity CRC and LD50 against HepG2 | Homo sapiens | 57 | cell-based format | MMV Malaria Box | ||
| 6. | ALA2028071 | F | MMV: Inhibition of Plasmodium falciparum 3D7 (EC50). | Plasmodium falciparum | 317 | organism-based format | MMV Malaria Box | ||
| 7. | ALA2028073 | F | MMV: Inhibition of Trypanosoma cruzi (Tulahuen C4 LacZ) (Chagas in vitro). | Trypanosoma cruzi | 400 | organism-based format | MMV Malaria Box | ||
| 8. | ALA2028074 | F | MMV: Inhibition of Trypanosoma brucei brucei (Squib 427) (HAT in vitro). | Trypanosoma brucei brucei | 400 | organism-based format | MMV Malaria Box | ||
| 9. | ALA2028075 | F | MMV: Inhibition of Trypanosoma brucei rhodesiense (STIB 900) (HAT in vitro). | Trypanosoma brucei rhodesiense | 400 | organism-based format | MMV Malaria Box | ||
| 10. | ALA2028076 | F | MMV: Inhibition of Leishmania infantum (MHOM/MA/BE/67) in vitro. | Leishmania infantum | 400 | organism-based format | MMV Malaria Box | ||
| 11. | ALA2028077 | T | MMV: Cytotoxicity against human fibroblasts (MRC-5) cells. | Homo sapiens | 400 | cell-based format | MMV Malaria Box | ||
| 12. | ALA2363023 | F | MMV: Toxicity @ 2.5 uM to newly transformed Schistosoma mansoni somules after 24 h on a scale of 0 (none) - 4 (most) as judged visually: includes short descriptors of effects (PMID:19597541). Caffrey group UCSF. | Schistosoma mansoni | 400 | organism-based format | MMV Malaria Box | ||
| 13. | ALA2363024 | F | MMV: Toxicity @ 2.5 uM to newly transformed Schistosoma mansoni somules after 48 h on a scale of 0 (none) - 4 (most) as judged visually: includes short descriptors of effects (PMID:19597541). Caffrey group UCSF. | Schistosoma mansoni | 400 | organism-based format | MMV Malaria Box | ||
| 14. | ALA2363025 | F | MMV: Toxicity @ 2.5 uM to newly transformed Schistosoma mansoni somules after 72 h on a scale of 0 (none) - 4 (most) as judged visually: includes short descriptors of effects (PMID:19597541). Caffrey group UCSF. | Schistosoma mansoni | 400 | organism-based format | MMV Malaria Box | ||
| 15. | ALA2363026 | F | MMV: Toxicity @ 5 uM to 4-5 Schistosoma mansoni adult males after 24 h on a scale of 0 (none) - 4 (most). Includes short descriptors of effects as judged visually (PMID:19597541). Only those Malaria box 'drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF. | Schistosoma mansoni | 41 | organism-based format | MMV Malaria Box | ||
| 16. | ALA2363027 | F | MMV: Toxicity @ 5 uM to 4-5 Schistosoma mansoni adult males after 48 h on a scale of 0 (none) - 4 (most). Includes short descriptors of effects as judged visually (PMID:19597541). Only those Malaria box 'drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF. | Schistosoma mansoni | 41 | organism-based format | MMV Malaria Box | ||
| 17. | ALA2363028 | F | MMV: Toxicity @ 5 uM to 4-5 Schistosoma mansoni adult males after 72 h on a scale of 0 (none) - 4 (most). Includes short descriptors of effects as judged visually (PMID:19597541). Only those Malaria box 'drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF. | Schistosoma mansoni | 40 | organism-based format | MMV Malaria Box | ||
| 18. | ALA2363029 | F | MMV: Motility assay. Percent change (relative to DMSO controls) @ 5 uM of movement of 4-5 Schistosoma mansoni adult males after 24 h as measured by the Consensus Voting Luminance Difference algorithm available on WormAssay (PMID:22303493). Occasional incongruence ocurrs between the motility scores and the visually adjudicated 'toxicity scores'. In these cases the 'toxicity score' should be prioritized. Only those Malaria box 'Drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF. | Schistosoma mansoni | 40 | organism-based format | MMV Malaria Box | ||
| 19. | ALA2363030 | F | MMV: Motility assay. Percent change (relative to DMSO controls) @ 5 uM of movement of 4-5 Schistosoma mansoni adult males after 48 h as measured by the Consensus Voting Luminance Difference algorithm available on WormAssay (PMID:22303493). Occasional incongruence ocurrs between the motility scores and the visually adjudicated 'toxicity scores'. In these cases the 'toxicity score' should be prioritized. Only those Malaria box 'Drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF. | Schistosoma mansoni | 41 | organism-based format | MMV Malaria Box | ||
| 20. | ALA2363031 | F | MMV: Motility assay. Percent change (relative to DMSO controls) @ 5 uM of movement of 4-5 Schistosoma mansoni adult males after 72 h as measured by the Consensus Voting Luminance Difference algorithm available on WormAssay (PMID:22303493). Occasional incongruence ocurrs between the motility scores and the visually adjudicated 'toxicity scores'. In these cases the 'toxicity score' should be prioritized. Only those Malaria box 'Drug-like' cpds yielding the most severe phenotypes vs. somules were tested. Caffrey group UCSF. | Schistosoma mansoni | 40 | organism-based format | MMV Malaria Box |
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