# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2033851 | B | Inhibition of EGFR L858R/T790M mutant-mediated Erk phosphorylation in human NCI-H1975 cells up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA2034006 | B | Inhibition of EGFR del E746-A750 mutant-mediated Akt phosphorylation in human HCC827 cells up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA2034008 | B | Inhibition of EGFR del E746-A750 mutant-mediated Erk phosphorylation in human HCC827 cells up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA2034010 | B | Inhibition of EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as change in EGFR level up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA2034012 | B | Inhibition of EGFR del E746-A750 mutant in human HCC827 cells assessed as change in EGFR level up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA2034014 | B | Inhibition of EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as change in Akt level up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA2034016 | B | Inhibition of EGFR del E746-A750 mutant in human HCC827 cells assessed as change in Akt level up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA2034018 | B | Inhibition of EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as change in Erk level up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA2034020 | B | Inhibition of EGFR del E746-A750 mutant in human HCC827 cells assessed as change in Erk level up to 50 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA2034021 | B | Inhibition of EGFR in human A549 cells harboring k-Ras mutant | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA2034022 | B | Inhibition of EGFR overexpressed in human A431 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA2034023 | F | Antiproliferative activity against human HCC827 cells harboring EGFR del E746-A750 mutant after 72 hrs by MTS assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
13. | ALA2034024 | F | Antiproliferative activity against human NCI-H1975 cells harboring EGFR L858R/T790M mutant after 72 hrs by MTS assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
14. | ALA2034025 | F | Antiproliferative activity against human A431 cells overexpressing EGFR after 72 hrs by MTS assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
15. | ALA2034026 | F | Antiproliferative activity against human A549 cells expressing wild type EGFR coexpressing k-Ras mutant after 72 hrs by MTS assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
16. | ALA2034027 | A | Antiproliferative activity against human HL7702 cells expressing wilt type EGFR after 72 hrs by MTS assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
17. | ALA2034028 | F | Ratio of WZ4002 IC50 to compound IC50 for human NCI-H1975 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
18. | ALA2034029 | F | Induction of apoptosis in human HCC827 cells harboring EGFR del E746-A750 mutant after 72 hrs by flow cytometry assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA2034030 | F | Induction of apoptosis in human NCI-H1975 cells harboring EGFR L858R/T790M mutant after 72 hrs by flow cytometry assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA2034031 | F | Induction of Cell cycle arrest in human HCC827 cells harboring EGFR del E746-A750 mutant assessed as G1 phase cells after 24 hrs by flow cytometry assay | Homo sapiens | 2 | cell-based format | Scientific Literature |