# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2034442 | F | Cytoprotective activity in hamster HIT-T15 cells assessed as inhibition of serum starvation-induced cell death at 1 to 100 nM after 24 hrs by MTT assay relative to control | Mesocricetus auratus | 24 | cell-based format | Scientific Literature | ||
2. | ALA2034443 | F | Cytoprotective activity in hamster HIT-T15 cells assessed as inhibition of IFN-gamma/TNFalpha/IL1beta-induced cell death at 1 to 100 nM after 24 hrs by MTT assay relative to control | Mesocricetus auratus | 28 | cell-based format | Scientific Literature | ||
3. | ALA2032554 | F | Antiapoptotic activity in hamster HIT-T15 cells assessed as reduction in IFN-gamma/TNFalpha/IL1beta-induced apoptosis at 1 nM after 24 hrs by Hoechst staining relative to control | Mesocricetus auratus | 4 | cell-based format | Scientific Literature | ||
4. | ALA2032555 | F | Antiapoptotic activity in hamster HIT-T15 cells assessed as reduction in IFN-gamma/TNFalpha/IL1beta-induced apoptosis at 10 nM after 24 hrs by Hoechst staining relative to control | Mesocricetus auratus | 5 | cell-based format | Scientific Literature | ||
5. | ALA2032556 | F | Antiapoptotic activity in hamster HIT-T15 cells assessed as reduction in IFN-gamma/TNFalpha/IL1beta-induced apoptosis at 100 nM after 24 hrs by Hoechst staining relative to control | Mesocricetus auratus | 5 | cell-based format | Scientific Literature | ||
6. | ALA2032557 | F | Cytoprotective activity in human pancreatic islet cells assessed as inhibition of serum starvation-induced cell death at 10 to 100 nM after 72 hrs by MTT assay relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
7. | ALA2032558 | F | Cytoprotective activity in human pancreatic islet cells assessed as inhibition of IFN-gamma/TNFalpha/IL1beta-induced cell death at 10 to 100 nM after 72 hrs by MTT assay relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
8. | ALA2032560 | F | Cytoprotective activity in hamster HIT-T15 cells assessed as inhibition of serum starvation-induced cell death after 24 hrs by MTT assay relative to control | Mesocricetus auratus | 3 | cell-based format | Scientific Literature | ||
9. | ALA2032561 | F | Cytoprotective activity in hamster HIT-T15 cells assessed as inhibition of IFN-gamma/TNFalpha/IL1beta-induced cell death after 24 hrs by MTT assay relative to control | Mesocricetus auratus | 3 | cell-based format | Scientific Literature | ||
10. | ALA2032562 | F | Antidiabetic activity in neonatal Sprague-Dawley rat assessed as inhibition of STZ-induced mortality at 30 nmol/kg, sc administered on day 2 post STZ-challenge measured on day 9 (Rvb = 52%) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
11. | ALA2032563 | F | Antidiabetic activity in neonatal Sprague-Dawley rat assessed as inhibition of STZ-induced mortality at 100 nmol/kg, sc administered on day 2 post STZ-challenge measured on day 9 (Rvb = 52%) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
12. | ALA2032564 | F | Antidiabetic activity in neonatal Sprague-Dawley rat assessed as decrease in STZ-induced plasma glucose level at 30 nmol/kg, sc administered from day 2 to day 9 post STZ-challenge measured after 70 days by colorimetry relative to control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
13. | ALA2032653 | F | Antidiabetic activity in neonatal Sprague-Dawley rat assessed as decrease in STZ-induced plasma glucose level at 100 nmol/kg, sc administered from day 2 to day 9 post STZ-challenge measured after 70 days by colorimetry by relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA2032654 | F | Antidiabetic activity in neonatal Sprague-Dawley rat assessed as inhibition of STZ-induced decrease in plasma insulin level at 30 nmol/kg, sc administered from day 2 to day 9 post STZ-challenge measured after 70 days by RIA relative to control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
15. | ALA2032655 | F | Antidiabetic activity in neonatal Sprague-Dawley rat assessed as inhibition of STZ-induced decrease in plasma insulin level at 100 nmol/kg, sc administered from day 2 to day 9 post STZ-challenge measured after 70 days by RIA by relative to control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
16. | ALA2032656 | F | Antidiabetic activity in neonatal Sprague-Dawley rat assessed as inhibition of STZ-induced decrease in pancreatic insulin level at 30 nmol/kg, sc administered from day 2 to day 9 post STZ-challenge measured after 70 days by RIA relative to control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
17. | ALA2032657 | F | Antidiabetic activity in neonatal Sprague-Dawley rat assessed as inhibition of STZ-induced decrease in pancreatic insulin level at 100 nmol/kg, sc administered from day 2 to day 9 post STZ-challenge measured after 70 days by RIA by relative to control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
18. | ALA2032658 | F | Cytoprotective activity in human EPC assessed as decrease in H2O2-induced ROS production after 2 hrs by DCF-DA flow cytometry assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
19. | ALA2032659 | B | Inhibition of Rac1 activation | 2 | single protein format | Scientific Literature | |||
20. | ALA2032661 | F | Cytoprotective activity in human EPC assessed as decrease in H2O2-induced senescence associated beta-galactosidase positive cells at 10 uM after 24 hrs | Homo sapiens | 2 | assay format | Scientific Literature |