# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2032679 | B | Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon and Line-Weaver Burk plot analysis at pH 5 | Homo sapiens | 9 | single protein format | Scientific Literature | ||
2. | ALA2032680 | B | Inhibition of human lysosomal alpha-glucosidase using 4-methylumbelliferyl alpha-D-glucopyranoside as substrate at 200 uM by fluorimetric analysis | Homo sapiens | 19 | single protein format | Scientific Literature | ||
3. | ALA2032681 | B | Inhibition of human lysosomal alpha-galactosidase using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at 200 uM by fluorimetric analysis | Homo sapiens | 19 | assay format | Scientific Literature | ||
4. | ALA2032682 | B | Inhibition of human lysosomal beta-galactosidase using 4-methylumbelliferyl beta-Dgalactopyranoside as substrate at 200 uM by fluorimetric analysis | Homo sapiens | 19 | single protein format | Scientific Literature | ||
5. | ALA2032683 | B | Inhibition of human cytosolic beta-glucosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by fluorimetric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA2032684 | B | Thermal denaturation of human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate assessed as change in melting temperature at 100 uM and pH 7 | Homo sapiens | 19 | single protein format | Scientific Literature | ||
7. | ALA2032685 | B | Activation of intracellular glucocerebrosidase p.N370S mutant in gaucher patient fibroblast using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate assessed as concentration at which 50% of maximum increase in activity | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
8. | ALA2032686 | B | Activation of intracellular glucocerebrosidase p.N370S mutant in gaucher patient fibroblast using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
9. | ALA2032687 | B | Activation of intracellular glucocerebrosidase p.L444P mutant in gaucher patient fibroblast using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate assessed as concentration at which 50% of maximum increase in activity | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
10. | ALA2032688 | B | Activation of intracellular glucocerebrosidase p.L444P mutant in gaucher patient fibroblast using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
11. | ALA2032689 | B | Activation of beta-N-acetyl hexosaminidase in gaucher patient fibroblast using 4-methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate | Homo sapiens | 1 | assay format | Scientific Literature | ||
12. | ALA2032691 | A | Cytotoxicity against gaucher patient fibroblast assessed as decrease in cell viability at 10 uM after 5 days by alamar blue assay | Homo sapiens | 1 | cell-based format | Scientific Literature |