# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2034241 | F | Agonist activity at Rev-erbalpha assessed as repression of transcription at 10 uM by luciferase-reporter gene assay relative to control | 51 | ALA2029304 | assay format | Scientific Literature | ||
2. | ALA2034242 | F | Agonist activity at Rev-erbalpha assessed as repression of transcription by luciferase-reporter gene assay | 51 | ALA2029304 | assay format | Scientific Literature | ||
3. | ALA2034243 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA2029304 | organism-based format | Scientific Literature | |
4. | ALA2034244 | A | Plasma clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA2029304 | organism-based format | Scientific Literature | |
5. | ALA2034245 | A | Volume of distribution in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA2029304 | organism-based format | Scientific Literature | |
6. | ALA2034246 | A | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg by LC-MS/MS analysis | Rattus norvegicus | 5 | ALA2029304 | organism-based format | Scientific Literature | |
7. | ALA2034247 | A | Plasma concentration in C57Bl6 mouse at 10 mg/kg, ip after 2 hrs by LC-MS/MS analysis | Mus musculus | 5 | ALA2029304 | organism-based format | Scientific Literature | |
8. | ALA2034248 | A | Drug uptake in C57Bl6 mouse brain at 10 mg/kg, ip after 2 hrs by LC-MS/MS analysis | Mus musculus | 5 | ALA2029304 | organism-based format | Scientific Literature | |
9. | ALA2034249 | A | Brain penetration in C57Bl6 mouse at 10 mg/kg, ip after 2 hrs by LC-MS/MS analysis | Mus musculus | 5 | ALA2029304 | organism-based format | Scientific Literature | |
10. | ALA4727677 | B | Agonist activity at Rev-Erb alpha (unknown origin) by FRET assay | Homo sapiens | 17 | ALA4725320 | single protein format | Scientific Literature | |
11. | ALA4727678 | B | Agonist activity at Rev-Erb alpha (unknown origin) by BMAL1-luciferase reporter assay | Homo sapiens | 4 | ALA4725320 | single protein format | Scientific Literature |