# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2039462 | B | Inhibition of Actinomadura sp. R39 PBP using S2d as substrate assessed as residual activity at 1 mM incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry in presence of triton X 100 | Actinomadura sp. R39 | 5 | ALA2034818 | single protein format | Scientific Literature | |
2. | ALA2039465 | B | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2x using S2d as substrate assessed as residual activity at 1 mM incubated for 60 mins prior to substrate addition by DTNB-based spectrophotometry in presence of triton X 100 | Streptococcus pneumoniae R6 | 4 | ALA2034818 | single protein format | Scientific Literature | |
3. | ALA2039467 | B | Inhibition of Streptococcus pneumoniae PBP1b assessed as residual activity at 1mM incubated for 60 mins prior to fluoresceyl-ampicillin labelling measured after 20 mins by SDS-PAGE analysis in the presence of triton X 100 | Streptococcus pneumoniae | 11 | ALA2034818 | assay format | Scientific Literature | |
4. | ALA2039472 | B | Inhibition of Streptococcus pneumoniae PBP1b using PATP thioester as substrate assessed as residual activity at 100 uM incubated for 60 mins prior to substrate addition by DNTB-based spectrophotometry in the presence of triton X 100 | Streptococcus pneumoniae | 12 | ALA2034818 | assay format | Scientific Literature | |
5. | ALA2039473 | B | Inhibition of penicillin-resistant Staphylococcus aureus PBP2a assessed as residual activity at 1 mM incubated for 60 mins prior to prior to fluoresceyl-ampicillin labelling measured after 20 mins by SDS-PAGE analysis | Staphylococcus aureus | 20 | ALA2034818 | assay format | Scientific Literature | |
6. | ALA2039474 | B | Inhibition of penicillin-resistant Enterococcus faecium PBP5fm assessed as residual activity at 1 mM incubated for 60 mins prior to prior to fluoresceyl-ampicillin labelling measured after 20 mins by SDS-PAGE analysis | Enterococcus faecium | 20 | ALA2034818 | assay format | Scientific Literature | |
7. | ALA2039476 | B | Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2x using S2d as substrate assessed as residual activity at 1 mM incubated for 4 hrs prior to substrate addition by DNTB-based spectrophotometry in the presence of triton X 100 | Streptococcus pneumoniae | 9 | ALA2034818 | single protein format | Scientific Literature |