# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2038927 | ADME | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg | Rattus norvegicus | 5 | ALA2034937 | organism-based format | Scientific Literature | |
2. | ALA2039030 | Functional | Antagonist activity at EP1 receptor in human U2OS cells expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs by FLIPR assay | Homo sapiens | 2 | ALA2034937 | cell-based format | Scientific Literature | |
3. | ALA2039040 | ADME | Half life in Sprague-Dawley rat at 1 mg/kg, iv | Rattus norvegicus | 5 | ALA2034937 | organism-based format | Scientific Literature | |
4. | ALA2039041 | ADME | Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po | Rattus norvegicus | 5 | ALA2034937 | organism-based format | Scientific Literature | |
5. | ALA2039057 | ADME | Dose-normalized AUC in Sprague-Dawley rat at 2 mg/kg, po | Rattus norvegicus | 5 | ALA2034937 | organism-based format | Scientific Literature | |
6. | ALA2039058 | Functional | Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs by FLIPR assay | Rattus norvegicus | 5 | ALA2034937 | cell-based format | Scientific Literature | |
7. | ALA2039059 | Functional | Antagonist activity at human EP3c receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced calcium mobilization after 24 hrs by FLIPR assay | Homo sapiens | 5 | ALA2034937 | cell-based format | Scientific Literature |