| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2038008 | B | Inhibition of N-terminal His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-coupled chemiluminescence assay | Homo sapiens | 47 | assay format | Scientific Literature | ||
| 2. | ALA2038009 | B | Inhibition of N-terminal His-tagged human PIM2 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-coupled chemiluminescence assay | Homo sapiens | 47 | assay format | Scientific Literature | ||
| 3. | ALA2038010 | B | Inhibition of N-terminal His-tagged human PIM3 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-coupled chemiluminescence assay | Homo sapiens | 47 | assay format | Scientific Literature | ||
| 4. | ALA2038011 | B | Inhibition of N-terminal MBP-tagged human alpha2beta2 CK2 expressed in Escherichia coli using casein as substrate after 1 to 2 hrs by luciferasse-luciferin-coupled chemiluminescence assay | Homo sapiens | 47 | assay format | Scientific Literature | ||
| 5. | ALA2038012 | A | Permeability of the compound across dog MDCK cells | Canis lupus familiaris | 24 | cell-based format | Scientific Literature | ||
| 6. | ALA2038013 | B | Inhibition of PIM-mediated BAD S112 phosphorylation in human HEL92.1.7 cells after overnight incubation by ELISA | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA2038014 | A | Plasma concentration in mouse at 100 mg/kg, po after 1 hr | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 8. | ALA2038015 | A | Plasma concentration in mouse at 100 mg/kg, po after 4 hrs | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 9. | ALA2038016 | A | Clearance in rat at 2.5 mg/kg | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA2038155 | A | Volume of distribution in rat at 2.5 mg/kg | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA2038156 | A | Half life in rat at 2.5 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA2038157 | A | Half life in rat at 2.5 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA2038158 | A | Oral bioavailability in rat at 2.5 mg/kg | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA2038159 | A | Cmax in rat at 2.5 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA2038160 | A | Cmax in rat at 2.5 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA2038161 | A | Dose normalised AUC in rat at 2.5 mg/kg, iv | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA2038162 | A | Dose normalised AUC in rat at 2.5 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA2038172 | B | Selectivity ratio of IC50 for N-terminal MBP-tagged human alpha2beta2 CK2 to IC50 for N-terminal His-tagged human PIM1 | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 19. | ALA2038173 | B | Selectivity ratio of IC50 for N-terminal MBP-tagged human alpha2beta2 CK2 to IC50 for N-terminal His-tagged human PIM3 | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 20. | ALA4044916 | B | Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysis | Homo sapiens | 31 | single protein format | Scientific Literature |
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