# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2037944 | Functional | Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation | Homo sapiens | 37 | ALA2034879 | cell-based format | Scientific Literature | |
2. | ALA2037945 | Functional | Agonist activity at human GPR109b | Homo sapiens | 7 | ALA2034879 | assay format | Scientific Literature | |
3. | ALA2037946 | Functional | Agonist activity at rat GPR109a | Rattus norvegicus | 7 | ALA2034879 | assay format | Scientific Literature | |
4. | ALA2037947 | Functional | Agonist activity at mouse GPR109a | Mus musculus | 7 | ALA2034879 | assay format | Scientific Literature | |
5. | ALA2037948 | Functional | Agonist activity at dog GPR109a | Canis lupus familiaris | 7 | ALA2034879 | assay format | Scientific Literature | |
6. | ALA2037949 | Functional | Antidyslipidemic activity in fasted Sprague-Dawley rat assessed as reduction in free fatty acid level in plasma at 1 mg/kg, po after 1 hr relative to vehicle-treated control | Rattus norvegicus | 5 | ALA2034879 | organism-based format | Scientific Literature | |
7. | ALA2037950 | Functional | Antidyslipidemic activity in fasted Sprague-Dawley rat assessed as reduction in triglyceride level in plasma at 1 mg/kg, po after 1 hr relative to vehicle-treated control | Rattus norvegicus | 5 | ALA2034879 | organism-based format | Scientific Literature | |
8. | ALA2037957 | Functional | Antidyslipidemic activity in fasted beagle dog assessed as reduction in free fatty acid level in plasma at 0.3 mg/kg, po after 1 hr relative to vehicle-treated control | Canis lupus familiaris | 1 | ALA2034879 | organism-based format | Scientific Literature | |
9. | ALA2037960 | Functional | Antidyslipidemic activity in po dosed fasted beagle dog assessed as reduction in free fatty acid level in plasma relative to vehicle-treated control | Canis lupus familiaris | 1 | ALA2034879 | organism-based format | Scientific Literature | |
10. | ALA2037962 | Toxicity | Nephrotoxicity in CD1 mouse assessed as acute renal necrosis | Mus musculus | 1 | ALA2034879 | organism-based format | Scientific Literature | |
11. | ALA2037963 | Toxicity | Nephrotoxicity in CD1 mouse assessed as increase in serum blood urea nitrogen level at 100 mg/kg | Mus musculus | 3 | ALA2034879 | organism-based format | Scientific Literature | |
12. | ALA2037964 | Toxicity | Nephrotoxicity in CD1 mouse assessed as increase in creatinine level at 100 mg/kg | Mus musculus | 3 | ALA2034879 | organism-based format | Scientific Literature | |
13. | ALA2038338 | Toxicity | Nephrotoxicity in rat assessed as increase in serum blood urea nitrogen level | Rattus norvegicus | 3 | ALA2034879 | organism-based format | Scientific Literature | |
14. | ALA2038339 | Toxicity | Nephrotoxicity in rat assessed as increase in creatinine level | Rattus norvegicus | 3 | ALA2034879 | organism-based format | Scientific Literature | |
15. | ALA5243292 | Binding | Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | Homo sapiens | 7 | ALA5241112 | cell-based format | Scientific Literature | |
16. | ALA5243293 | Binding | Agonist activity at human HCA2 expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Lance cAMP assay | Homo sapiens | 7 | ALA5241112 | cell-based format | Scientific Literature |