# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2037944 | F | Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
2. | ALA2037945 | F | Agonist activity at human GPR109b | Homo sapiens | 7 | assay format | Scientific Literature | ||
3. | ALA2037946 | F | Agonist activity at rat GPR109a | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
4. | ALA2037947 | F | Agonist activity at mouse GPR109a | Mus musculus | 7 | assay format | Scientific Literature | ||
5. | ALA2037948 | F | Agonist activity at dog GPR109a | Canis lupus familiaris | 7 | assay format | Scientific Literature | ||
6. | ALA2037949 | F | Antidyslipidemic activity in fasted Sprague-Dawley rat assessed as reduction in free fatty acid level in plasma at 1 mg/kg, po after 1 hr relative to vehicle-treated control | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
7. | ALA2037950 | F | Antidyslipidemic activity in fasted Sprague-Dawley rat assessed as reduction in triglyceride level in plasma at 1 mg/kg, po after 1 hr relative to vehicle-treated control | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
8. | ALA2037958 | F | Antidyslipidemic activity in fasted beagle dog assessed as reduction in free fatty acid level in plasma at 2 mg/kg, po after 1 hr relative to vehicle-treated control | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
9. | ALA2037963 | T | Nephrotoxicity in CD1 mouse assessed as increase in serum blood urea nitrogen level at 100 mg/kg | Mus musculus | 3 | organism-based format | Scientific Literature | ||
10. | ALA2037964 | T | Nephrotoxicity in CD1 mouse assessed as increase in creatinine level at 100 mg/kg | Mus musculus | 3 | organism-based format | Scientific Literature | ||
11. | ALA2038338 | T | Nephrotoxicity in rat assessed as increase in serum blood urea nitrogen level | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
12. | ALA2038339 | T | Nephrotoxicity in rat assessed as increase in creatinine level | Rattus norvegicus | 3 | organism-based format | Scientific Literature |