| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2037944 | F | Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 2. | ALA2037945 | F | Agonist activity at human GPR109b | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 3. | ALA2037946 | F | Agonist activity at rat GPR109a | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
| 4. | ALA2037947 | F | Agonist activity at mouse GPR109a | Mus musculus | 7 | assay format | Scientific Literature | ||
| 5. | ALA2037948 | F | Agonist activity at dog GPR109a | Canis lupus familiaris | 7 | assay format | Scientific Literature | ||
| 6. | ALA2037949 | F | Antidyslipidemic activity in fasted Sprague-Dawley rat assessed as reduction in free fatty acid level in plasma at 1 mg/kg, po after 1 hr relative to vehicle-treated control | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 7. | ALA2037950 | F | Antidyslipidemic activity in fasted Sprague-Dawley rat assessed as reduction in triglyceride level in plasma at 1 mg/kg, po after 1 hr relative to vehicle-treated control | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 8. | ALA2037955 | F | Antidyslipidemic activity in fasted beagle dog assessed as reduction in free fatty acid level in plasma at 1 mg/kg, po after 1 hr relative to vehicle-treated control | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA2038314 | A | AUC (0 to 24 hrs) in Sprague-Dawley rat at 5 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2038315 | A | Oral bioavailability in Sprague-Dawley rat at 5 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA2038316 | F | Antidyslipidemic activity in po dosed fasted Sprague-Dawley rat assessed as reduction in free fatty acid level in plasma | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA2038317 | F | Antidyslipidemic activity in po dosed fasted Sprague-Dawley rat assessed as reduction in triglyceride level in plasma | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2038318 | F | Antidyslipidemic activity in fasted Sprague-Dawley rat assessed as reduction in free fatty acid level in plasma at 3 mg/kg, po up to 2 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA2038319 | F | Antidyslipidemic activity in fasted Sprague-Dawley rat assessed as reduction in free fatty acid level in plasma at 3 mg/kg, po after 2 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA2038320 | T | Toxicity in fasted beagle dog assessed as flushing at 1 to 10 mg/kg, po | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA2038321 | T | Toxicity in fasted beagle dog assessed as change in skin colour at 1 to 10 mg/kg, po | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA2038322 | T | Toxicity in fasted beagle dog assessed as behavioural changes at 1 to 10 mg/kg, po | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA2038323 | T | Toxicity in fasted beagle dog assessed as increase in cutaneous blood flow at 30 mg/kg, po relative to control | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA2038324 | T | Toxicity in fasted beagle dog assessed as behavioural changes at 30 mg/kg, po relative to control | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA2038325 | T | Nephrotoxicity in CD1 mouse at 100 mg/kg, po administered qd for 5 days measured 2 hrs post-last dose | Mus musculus | 1 | organism-based format | Scientific Literature |
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