| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2044568 | F | Positive allosteric modulation of human muscarinic M1 receptor expressed in CHO-NFAT cells assessed as potentiation of acetylcholine-induced calcium flux after 1 hr by FLIPR assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA2044569 | F | Positive allosteric modulation of human muscarinic M1 receptor expressed in CHO-NFAT cells assessed as potentiation of acetylcholine-induced calcium flux after 1 hr by FLIPR assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA2044574 | A | Passive permeability of the compound assessed as P-glycoprotein-mediated drug transport | 4 | assay format | Scientific Literature | |||
| 4. | ALA2044577 | A | Plasma concentration in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 5. | ALA2044726 | A | Drug uptake in Sprague-Dawley rat brain at 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 6. | ALA2044727 | A | Ratio of drug level in brain to plasma in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 7. | ALA2044728 | A | Drug uptake in Sprague-Dawley rat cerebrospinal fluid at 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA2044729 | A | Ratio of drug uptake in Sprague-Dawley rat cerebrospinal fluid at 10 mg/kg, po to protein binding in rat plasma | Rattus norvegicus | 4 | organism-based format | Scientific Literature |
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