| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2050885 | B | Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 2. | ALA2050886 | B | Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA2050887 | B | Inhibition of mPGES-1 derived from LPS stimulated mouse RAW264.7 cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA2050888 | B | Inhibition of mPGES-1 derived from LPS stimulated mouse NIH3T3 cells microsomal fraction using PGH2 as substrate at 1 uM preincubated for 30 mins prior to substrate addition measured after 1 min by LC-MS/MS analysis relative to control | Mus musculus | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA2050889 | B | Inhibition of ovine COX1-mediated PGE2 synthesis using PGH2 as substrate at 1 uM by LC-MS/MS analysis relative to control | Ovis aries | 9 | single protein format | Scientific Literature | ||
| 6. | ALA2050890 | B | Inhibition of human recombinant COX2-mediated PGE2 synthesis using PGH2 as substrate at 1 uM by LC-MS/MS analysis relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 7. | ALA2050891 | A | Cytotoxicity against IL1beta and TNFalpha-stimulated human HeLa cells at 1 to 10 uM after 24 hrs by WST1 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA2050892 | B | Inhibition of mPGES-1 in IL1beta and TNFalpha-stimulated human HeLa cells assessed as PGE2 level after 24 hrs by LC-MS/MS analysis | Homo sapiens | 10 | cell-based format | Scientific Literature |
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