# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2049671 | B | Inhibition of glucan synthase in Candida albicans BWP17 membrane | Candida albicans | 24 | cell membrane format | Scientific Literature | ||
2. | ALA2049672 | F | Antifungal activity against Candida glabrata C624 by broth dilution method | Nakaseomyces glabratus | 24 | organism-based format | Scientific Literature | ||
3. | ALA2049673 | F | Antifungal activity against Candida albicans C693 by broth dilution method | Candida albicans | 24 | organism-based format | Scientific Literature | ||
4. | ALA2049674 | F | Antifungal activity against Candida albicans C43 by broth dilution method | Candida albicans | 8 | organism-based format | Scientific Literature | ||
5. | ALA2049675 | F | Antifungal activity against Candida albicans C43 by broth dilution method in presence of 25% human serum | Candida albicans | 3 | organism-based format | Scientific Literature | ||
6. | ALA2049676 | F | Antifungal activity against Candida albicans C375 by broth dilution method | Candida albicans | 8 | organism-based format | Scientific Literature | ||
7. | ALA2049677 | F | Antifungal activity against Aspergillus fumigatus ND158 by broth dilution method | Aspergillus fumigatus | 8 | organism-based format | Scientific Literature | ||
8. | ALA2049679 | A | Clearance in rat hepatocytes assessed per million cells | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
9. | ALA2049680 | A | AUC (0 to 6 hrs) in rat at 10 mg/kg, po | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
10. | ALA2049681 | F | Antifungal activity against Candida albicans C43 systemically infected in mouse assessed as reduction in fungal burden in kidney at 100 mg/kg, ip administered daily for 4 days relative to vehicle treated control | Candida albicans | 1 | organism-based format | Scientific Literature | ||
11. | ALA2049682 | F | Antifungal activity against Candida albicans C43 systemically infected in mouse assessed as reduction in fungal burden in kidney at 100 mg/kg, ip administered daily for 4 days relative to caspofungin | Candida albicans | 1 | organism-based format | Scientific Literature |