# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2049981 | B | Inhibition of Met-triggered cell scattering in HGF-stimulated MDCK cells preincubated for overnight before HGF challenge measured after 24 to 48 hrs | Canis lupus familiaris | 4 | ALA2046343 | cell-based format | Scientific Literature | |
2. | ALA2049982 | A | Cytotoxicity against MDCK cells at IC50 | Canis lupus familiaris | 3 | ALA2046343 | cell-based format | Scientific Literature | |
3. | ALA2049983 | F | Cytotoxicity against human GTL16 cells expressing MET assessed as inhibition of anchorage-independent cell growth treated every 3 days for 2 weeks by MTT assay | Homo sapiens | 3 | ALA2046343 | cell-based format | Scientific Literature | |
4. | ALA2049984 | B | Inhibition of HGF-induced Met phosphorylation at Tyr1234 and Tyr1235 in MDCK cells at 10 uM by immunoblotting | Canis lupus familiaris | 1 | ALA2046343 | cell-based format | Scientific Literature | |
5. | ALA2049985 | B | Inhibition of HGF-induced Met R998C mutant phosphorylation at Tyr1234 and Tyr1235 in human H1437 cells at 10 uM by immunoblotting | Homo sapiens | 1 | ALA2046343 | cell-based format | Scientific Literature | |
6. | ALA2049986 | F | Cytotoxicity against human NCI-H1437 cells assessed as inhibition of anchorage-independent cell growth treated every 3 days for 2 weeks by MTT assay | Homo sapiens | 1 | ALA2046343 | cell-based format | Scientific Literature |