| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2050325 | B | Inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins by scintillation counting | 11 | cell-based format | Scientific Literature | |||
| 2. | ALA2050382 | B | Noncompetitive inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells using S-adenosyl-L-methionine after 8 mins by double-reciprocal plot analysis | 1 | cell-based format | Scientific Literature | |||
| 3. | ALA2050383 | B | Noncompetitive inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells using histone H4 peptide after 8 mins by double-reciprocal plot analysis | 1 | cell-based format | Scientific Literature | |||
| 4. | ALA2050384 | B | Reversible inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells assessed as residual activity measured prior to dialysis using [14C]-S-adenosyl-L-methionine and histone H4 peptide at 20 uM measured after 72 hrs prior to dialysis by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 5. | ALA2050385 | B | Reversible inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells assessed as residual activity measured after dialysis using [14C]-S-adenosyl-L-methionine and histone H4 peptide at 20 uM measured after 72 hrs after dialysis by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 6. | ALA2050386 | B | Reversible inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells in time dependent inhibition protocol using [14C]-S-adenosyl-L-methionine and histone H4 peptide by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 7. | ALA2050387 | B | Inhibition of His-tagged PRMT1 Y148A mutant expressed in Escherichia coli BL21(DE3) cells assessed as residual activity using [14C]-S-adenosyl-L-methionine and histone H4 peptide at 4 uM measured after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 8. | ALA2050388 | B | Inhibition of His-tagged PRMT1 T81A mutant expressed in Escherichia coli BL21(DE3) cells assessed as residual activity using [14C]-S-adenosyl-L-methionine and histone H4 peptide at 4 uM measured after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 9. | ALA2050389 | B | Inhibition of His-tagged PRMT1 T292A mutant expressed in Escherichia coli BL21(DE3) cells assessed as residual activity using [14C]-S-adenosyl-L-methionine and histone H4 peptide at 4 uM measured after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 10. | ALA2050390 | B | Inhibition of His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells assessed as residual activity using [14C]-S-adenosyl-L-methionine and histone H4 peptide at 4 uM measured after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 11. | ALA2050391 | B | Inhibition of His-tagged PRMT1 Y152A mutant expressed in Escherichia coli BL21(DE3) cells assessed as residual activity using [14C]-S-adenosyl-L-methionine and histone H4 peptide at 4 uM measured after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 12. | ALA2050392 | B | Inhibition of His6X-tagged PRMT3 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 13. | ALA2050393 | B | Inhibition of His6X-tagged PRMT5 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 14. | ALA2050394 | B | Inhibition of His6X-tagged PRMT6 expressed in Escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H4 peptide after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 15. | ALA2050395 | B | Inhibition of GST-tagged CARM1 expressed in escherichia coli BL21(DE3) cells using [14C]-S-adenosyl-L-methionine and histone H3 peptide after 8 mins by scintillation counting | 1 | cell-based format | Scientific Literature | |||
| 16. | ALA2050396 | B | Selectivity index, ratio of IC50 for His6X-tagged PRMT3 to His6X-tagged PRMT1 | 1 | assay format | Scientific Literature | |||
| 17. | ALA2050397 | B | Selectivity index, ratio of IC50 for His6X-tagged PRMT5 to His6X-tagged PRMT1 | 1 | assay format | Scientific Literature | |||
| 18. | ALA2050398 | B | Selectivity index, ratio of IC50 for His6X-tagged PRMT6 to His6X-tagged PRMT1 | 1 | assay format | Scientific Literature | |||
| 19. | ALA2050399 | A | Cellular uptake in human HeLa cell nucleus after 6 hrs by bright field microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA2050400 | A | Cellular uptake in human HeLa cell cytoplasmic vesicles at 2 to 5 uM after 6 hrs by bright field microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!