# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2050419 | B | Inhibition of human recombinant HDAC6 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescence analysis | Homo sapiens | 46 | single protein format | Scientific Literature | ||
2. | ALA2050420 | B | Inhibition of human recombinant HDAC1 using Boc-lys(Ac)-AMC as substrate preincubated for 20 mins with substrate measured after 60 mins by fluorescence analysis | Homo sapiens | 46 | single protein format | Scientific Literature | ||
3. | ALA2050421 | B | Selectivity index, ratio of IC50 for human recombinant HDAC6 to IC50 for human recombinant HDAC1 | Homo sapiens | 37 | assay format | Scientific Literature | ||
4. | ALA2050422 | B | Inhibition of Bordetella sp. (strain FB188) N-terminus His-tagged HDAH expressed in Escherichia coli BL21 (DE3) up to 100 uM | Alcaligenaceae bacterium FB188 | 59 | assay format | Scientific Literature | ||
5. | ALA2050423 | B | Inhibition of Bordetella sp. (strain FB188) N-terminus His-tagged HDAH expressed in Escherichia coli BL21 (DE3) | Alcaligenaceae bacterium FB188 | 4 | assay format | Scientific Literature | ||
6. | ALA4679589 | B | Inhibition of recombinant full length C-terminal FLAG-tagged human HDAC6 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
7. | ALA4679590 | B | Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) co-expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
8. | ALA4679591 | B | Inhibition of recombinant full length C-terminal FLAG-tagged human HDAC2 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
9. | ALA4679592 | B | Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 expressed in baculovirus infected Sf9 cells using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by fluorescence based assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
10. | ALA4679593 | F | Growth inhibition of human HL-60 cells after 72 hrs by trypan blue dye based assay | Homo sapiens | 18 | cell-based format | Scientific Literature |