# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2051271 | B | Inhibition of human carbonic anhydrase 1 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay | Homo sapiens | 50 | ALA2046290 | single protein format | Scientific Literature | |
2. | ALA2051272 | B | Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay | Homo sapiens | 50 | ALA2046290 | single protein format | Scientific Literature | |
3. | ALA2051273 | B | Inhibition of human carbonic anhydrase 9 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay | Homo sapiens | 50 | ALA2046290 | single protein format | Scientific Literature | |
4. | ALA2051274 | B | Inhibition of human carbonic anhydrase 12 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay | Homo sapiens | 50 | ALA2046290 | single protein format | Scientific Literature | |
5. | ALA2051275 | B | Selectivity ratio of Ki for human carbonic anhydrase 2 to Ki for human carbonic anhydrase 9 | Homo sapiens | 50 | ALA2046290 | assay format | Scientific Literature | |
6. | ALA2051358 | F | Antiproliferative activity against human SKBR3 cells at 100 uM after 5 days by SRB assay under normoxic condition | Homo sapiens | 9 | ALA2046290 | cell-based format | Scientific Literature | |
7. | ALA2051359 | F | Antiproliferative activity against human MCF10A cells at 100 uM after 5 days by SRB assay under normoxic condition | Homo sapiens | 9 | ALA2046290 | cell-based format | Scientific Literature | |
8. | ALA2051360 | F | Antiproliferative activity against human ZR-75-1 cells at 100 uM after 5 days by SRB assay under normoxic condition | Homo sapiens | 9 | ALA2046290 | cell-based format | Scientific Literature | |
9. | ALA2051361 | F | Antiproliferative activity against human MDA-MB-361 cells at 100 uM after 5 days by SRB assay under normoxic condition | Homo sapiens | 9 | ALA2046290 | cell-based format | Scientific Literature | |
10. | ALA2051362 | F | Antiproliferative activity against human MCF7 cells after 5 days by SRB assay under hypoxic condition | Homo sapiens | 9 | ALA2046290 | cell-based format | Scientific Literature | |
11. | ALA2051363 | F | Antiproliferative activity against human MCF7 cells at 10 uM after 5 days by SRB assay under hypoxic condition | Homo sapiens | 9 | ALA2046290 | cell-based format | Scientific Literature | |
12. | ALA2051364 | F | Antiproliferative activity against human MCF7 cells at 30 uM after 5 days by SRB assay under hypoxic condition | Homo sapiens | 9 | ALA2046290 | cell-based format | Scientific Literature | |
13. | ALA2150240 | B | Inhibition of human recombinant cytosolic CA1 preincubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 11 | ALA2146379 | single protein format | Scientific Literature | |
14. | ALA2150241 | B | Inhibition of human recombinant cytosolic CA2 preincubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 11 | ALA2146379 | single protein format | Scientific Literature | |
15. | ALA2150242 | B | Inhibition of human recombinant transmembrane CA9 preincubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 11 | ALA2146379 | single protein format | Scientific Literature | |
16. | ALA2150243 | B | Inhibition of human recombinant transmembrane CA12 preincubated for 15 mins by stopped-flow CO2 hydration method | Homo sapiens | 11 | ALA2146379 | single protein format | Scientific Literature | |
17. | ALA2150244 | B | Ratio of Ki for human recombinant cytosolic CA2 to Ki for human recombinant transmembrane CA9 | Homo sapiens | 11 | ALA2146379 | assay format | Scientific Literature | |
18. | ALA2150245 | F | Antimetastatic activity against EGFP tagged human MDA-MB-231 cells expressing CA9 assessed as inhibition of cell migration under anoxic condition after 24 hrs by scratch-wound assay | Homo sapiens | 7 | ALA2146379 | cell-based format | Scientific Literature | |
19. | ALA2150246 | F | Antimetastatic activity against EGFP tagged human MDA-MB-231 cells expressing CA9 assessed as inhibition of cell migration under normoxic condition after 24 hrs by scratch-wound assay | Homo sapiens | 3 | ALA2146379 | cell-based format | Scientific Literature | |
20. | ALA2342096 | B | Inhibition of human carbonic anhydrase-12 | Homo sapiens | 65 | ALA2331360 | single protein format | Scientific Literature |