| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2051204 | B | Activation of proteasome in human HT1080 cells expressing FLAG-tagged cIAP1 assessed as induction of cIAP1 and CRABP-2 protein degradation at 0.1 to 10 uM after 6 hrs by Western blot analysis | Homo sapiens | 1 | subcellular format | Scientific Literature | ||
| 2. | ALA2051209 | B | Activation of proteasome in human IMR32 cells assessed as induction of cIAP1 and CRABP-2 protein degradation at 3 to 30 uM after 24 hrs by Western blot analysis | Homo sapiens | 3 | subcellular format | Scientific Literature | ||
| 3. | ALA2051210 | F | Antiproliferative activity against human IMR32 cells assessed as reduction of cell number at 30 uM after 24 to 72 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA2051211 | F | Induction of apoptosis in human IMR32 cells assessed as activation of caspase 3/7 after 24 hrs relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA2156770 | F | Induction of CRABP-2 degradation in human HT1080 cells at 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA2156780 | B | Induction of FLAG-tagged cIAP1 expressed in human HT1080 cells assessed as RARalpha degradation at 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA2188708 | B | Binding affinity to Flag-tagged cIAP1/CRABP2 expressed in human HT1080 cells assessed as induction in CRABP-2 degradation after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA2182114 | F | Induction of apoptosis in human HT1080 cells at 1 to 30 uM after 24 hrs by lactate dehydrogenase assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA2182115 | F | Induction of apoptosis in human HT1080 cells after 24 hrs by lactate dehydrogenase assay in presence of etoposide | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA2182116 | F | Induction of apoptosis in human HT1080 cells assessed as activation of caspase 3/7 at 30 uM after 24 hrs by fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA2182117 | F | Induction of apoptosis in human HT1080 cells assessed as activation of caspase 3/7 at 30 uM after 24 hrs by fluorescence assay in presence of etoposide | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA5241461 | B | Protac activity at cIAP1 (unknown origin)/CRABP-II (unknown origin) assessed as protein degradation | Homo sapiens | 1 | assay format | Scientific Literature |
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