| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2051552 | B | Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from human GPR40 receptor expressed in CHO cell membrane after 90 mins by liquid scintillation counting in the presence of 0.2% BSA | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 2. | ALA2051553 | B | Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from rat GPR40 receptor expressed in CHO cell membrane after 90 mins by liquid scintillation counting in the presence of 0.2% BSA | Rattus norvegicus | 21 | cell-based format | Scientific Literature | ||
| 3. | ALA2051554 | F | Agonist activity at human GPR40 receptor expressed in CHO cells assessed as increase in intracellular calcium level for 90 secs by FLIPR assay in the presence of 0.1% BSA | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 4. | ALA2051555 | A | Cytotoxicity against human HepG2 cells assessed as intracellular ATP level at 30 uM after 24 hrs by ATPlite assay relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 5. | ALA2051556 | A | Cytotoxicity against human HepG2 cells assessed as intracellular ATP level at 10 uM after 24 hrs by ATPlite assay relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 6. | ALA2051557 | A | Induction of apoptosis in human HepG2 cells assessed as caspase 3/7 activity at 30 uM after 24 hrs by caspase Glo assay relative to staurosporine | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 7. | ALA2051558 | A | Induction of apoptosis in human HepG2 cells assessed as caspase 3/7 activity at 10 uM after 24 hrs by caspase Glo assay relative to staurosporine | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 8. | ALA2051559 | P | Lipophilicity, log D of the compound by RP-HPLC analysis | 21 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA2051560 | F | Insulinotropic activity in rat INS1(833/15) cells assessed as increase in insulin secretion after 2 hrs by competitive enzyme immunoassay in the presence of 11 mM glucose | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2051561 | F | Insulinotropic activity in rat INS1(833/15) cells assessed as increase in insulin secretion at >0.1 uM after 2 hrs by competitive enzyme immunoassay in the presence of 11 mM glucose | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2051562 | F | Insulinotropic activity in rat INS1(833/15) cells assessed as increase in insulin secretion at 1 uM after 2 hrs by competitive enzyme immunoassay in the presence of >6 mM glucose | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2051563 | F | Insulinotropic activity in rat INS1(833/15) cells assessed as increase in insulin secretion at 1 uM after 2 hrs by competitive enzyme immunoassay in the presence of 1 mM glucose | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA2051564 | F | Insulinotropic activity in rat INS1(833/15) cells assessed as increase in insulin secretion at 1 uM after 2 hrs by competitive enzyme immunoassay in the presence of 4 mM glucose | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2051567 | F | Insulinotropic activity in rat INS1(833/15) cells assessed as increase in insulin secretion at 1 uM after 2 hrs by competitive enzyme immunoassay in the presence of 16 mM glucose | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2051678 | A | Metabolic stability in human hepatic microsomes | Homo sapiens | 14 | microsome format | Scientific Literature | ||
| 16. | ALA2051679 | A | Metabolic stability in rat hepatic microsomes | Rattus norvegicus | 14 | microsome format | Scientific Literature | ||
| 17. | ALA4650107 | B | Thermal Shift Assay. Domain start/stop: M626-G740 | Homo sapiens | 1,014 | single protein format | EUbOPEN Chemogenomic Library | ||
| 18. | ALA4725212 | T | Incucyte cell viability with HEK293T | Homo sapiens | 1,713 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 19. | ALA4725213 | T | Incucyte cell viability with human fibroblast | Homo sapiens | 1,718 | cell-based format | EUbOPEN Chemogenomic Library | ||
| 20. | ALA4725214 | T | Incucyte cell viability with U2OS | Homo sapiens | 1,712 | cell-based format | EUbOPEN Chemogenomic Library |
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