| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2060896 | A | Plasma clearance in rat | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 2. | ALA2320092 | F | Antipsychotic activity in Sprague-Dawley rat assessed as reversal of amphetamine-induced hyperlocomotion at 100 mg/kg, ip after 90 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA2320093 | F | Antipsychotic activity in Sprague-Dawley rat assessed as reversal of amphetamine-induced hyperlocomotion at 56.6 mg/kg, ip after 90 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA2320094 | F | Antipsychotic activity in Sprague-Dawley rat assessed as reversal of amphetamine-induced hyperlocomotion at 30 mg/kg, ip after 90 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA2320095 | F | Antipsychotic activity in Sprague-Dawley rat assessed as reversal of amphetamine-induced hyperlocomotion at 10 mg/kg, ip after 90 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA2320096 | F | Antipsychotic activity in Sprague-Dawley rat assessed as reversal of amphetamine-induced hyperlocomotion at 3 mg/kg, ip after 90 mins | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA2320097 | A | Ratio of drug level in brain to plasma in rat at 10 mg/kg, ip up to 6 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA2320098 | A | Drug level in rat brain at 10 mg/kg, ip up to 6 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA2320099 | A | AUC in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA2320100 | A | Systemic plasma concentration in rat at 10 mg/kg, ip up to 6 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA2320101 | A | Mean residence time in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA2320102 | A | Volume of distribution at steady state in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA2320103 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA2320104 | A | Clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA2320105 | B | Binding affinity to human DAT at 10 uM by radioligand binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA2320106 | B | Binding affinity to rat GABAA receptor at 10 uM by radioligand binding assay | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 17. | ALA2320107 | B | Positive allosteric modulation of rat muscarinic M5 receptor assessed as acetylcholine response | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
| 18. | ALA2320108 | F | Positive allosteric modulation of human muscarinic M5 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated for 144 secs prior to acetylcholine addition measured for 5 mins by Fluo-4-AM based calcium mobilization assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA2320109 | B | Positive allosteric modulation of rat muscarinic M3 receptor assessed as acetylcholine response | Rattus norvegicus | 2 | single protein format | Scientific Literature | ||
| 20. | ALA2320110 | F | Positive allosteric modulation of human muscarinic M3 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated for 144 secs prior to acetylcholine addition measured for 5 mins by Fluo-4-AM based calcium mobilization assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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