# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2061324 | B | Inhibition of squalene synthase in rat hepatic cells | Rattus norvegicus | 44 | cell-based format | Scientific Literature | ||
2. | ALA2061325 | F | Inhibition of cholesterol synthesis in rat hepatocytes assessed as formation of cholesterol using [14C]mevalonolactone as substrate after 1 hr by radioactivity assay | Rattus norvegicus | 41 | cell-based format | Scientific Literature | ||
3. | ALA2061365 | F | Inhibition of cholesterol synthesis in Wistar rat liver assessed as reduction of [14C]-cholesterol level at 3 mg/kg, po administered as single dose measured after 1 hr by liquid scintillation counting | Rattus norvegicus | 27 | organism-based format | Scientific Literature | ||
4. | ALA2061366 | F | Lipid lowering effect in marmosets assessed as reduction in plasma total cholesterol level at 100 mg/kg, po administered once daily for 7 days | marmosets | 6 | organism-based format | Scientific Literature | ||
5. | ALA2061367 | F | Lipid lowering effect in marmosets assessed as reduction in plasma HDL-cholesterol level at 100 mg/kg, po administered once daily for 7 days | marmosets | 6 | organism-based format | Scientific Literature | ||
6. | ALA2061368 | F | Lipid lowering effect in marmosets assessed as reduction in plasma non HDL-cholesterol level at 100 mg/kg, po administered once daily for 7 days | marmosets | 6 | organism-based format | Scientific Literature | ||
7. | ALA2061369 | F | Lipid lowering effect in marmosets assessed as reduction in plasma triglyceride level at 100 mg/kg, po administered once daily for 7 days | marmosets | 6 | organism-based format | Scientific Literature |