# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2061531 | F | Antiproliferative activity against human K562 cells by MTT assay | Homo sapiens | 15 | ALA2057091 | cell-based format | Scientific Literature | |
2. | ALA2061532 | F | Antiproliferative activity against human COLO205 cells by MTT assay | Homo sapiens | 15 | ALA2057091 | cell-based format | Scientific Literature | |
3. | ALA2061533 | F | Antiproliferative activity against human MDA-MB-231 cells by MTT assay | Homo sapiens | 15 | ALA2057091 | cell-based format | Scientific Literature | |
4. | ALA3830929 | B | Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assay | Homo sapiens | 31 | ALA3826913 | single protein format | Scientific Literature | |
5. | ALA3830930 | B | Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrate addition measured after 30 mins | Homo sapiens | 31 | ALA3826913 | cell-based format | Scientific Literature | |
6. | ALA3830931 | B | Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assay | Homo sapiens | 31 | ALA3826913 | single protein format | Scientific Literature | |
7. | ALA3829027 | B | Inhibition of human PARP-2 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assay | Homo sapiens | 17 | ALA3826913 | single protein format | Scientific Literature | |
8. | ALA3829028 | B | Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells at 1 uM preincubated for 2 hrs followed by substrate addition measured after 30 mins | Homo sapiens | 77 | ALA3826913 | cell-based format | Scientific Literature | |
9. | ALA3829126 | B | Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells at 100 nM preincubated for 2 hrs followed by substrate addition measured after 30 mins | Homo sapiens | 77 | ALA3826913 | cell-based format | Scientific Literature | |
10. | ALA3829127 | B | Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells at 10 nM preincubated for 2 hrs followed by substrate addition measured after 30 mins | Homo sapiens | 77 | ALA3826913 | cell-based format | Scientific Literature | |
11. | ALA3829128 | F | Antiproliferative activity against human HT-29 cells at 100 uM by MTS assay | Homo sapiens | 41 | ALA3826913 | cell-based format | Scientific Literature | |
12. | ALA3829129 | F | Antiproliferative activity against human HT-29 cells at 10 uM by MTS assay | Homo sapiens | 41 | ALA3826913 | cell-based format | Scientific Literature | |
13. | ALA3829130 | F | Antiproliferative activity against human HT-29 cells at 1 uM by MTS assay | Homo sapiens | 41 | ALA3826913 | cell-based format | Scientific Literature | |
14. | ALA3879443 | B | Non-competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase type 1 using p-nitro-phenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins followed by substrate addition measured after 5 mins every 10 secs by Lineweaver-Burk plot analysis | Saccharomyces cerevisiae | 2 | ALA3877317 | assay format | Scientific Literature | |
15. | ALA3879444 | B | Reversible inhibition of Saccharomyces cerevisiae alpha-glucosidase type 1 at 8 to 24 uM using p-nitro-phenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins followed by substrate addition measured after 5 mins every 10 secs | Saccharomyces cerevisiae | 2 | ALA3877317 | assay format | Scientific Literature | |
16. | ALA3879445 | B | Inhibition of Saccharomyces cerevisiae alpha-glucosidase type 1 using p-nitro-phenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins followed by substrate addition measured after 5 mins every 10 secs | Saccharomyces cerevisiae | 9 | ALA3877317 | assay format | Scientific Literature | |
17. | ALA3879446 | B | Binding affinity to Saccharomyces cerevisiae alpha-glucosidase type 1 assessed as fluorescence quenching by measuring relative fluorescence intensity at 60 uM by fluorescence spectrophotometric method | Saccharomyces cerevisiae | 1 | ALA3877317 | assay format | Scientific Literature | |
18. | ALA3879448 | B | Effect on Saccharomyces cerevisiae alpha-glucosidase type 1 protein conformation assessed as red shift at 10 to 60 uM by fluorescence spectrophotometric method | Saccharomyces cerevisiae | 1 | ALA3877317 | assay format | Scientific Literature | |
19. | ALA3879450 | B | Effect on Saccharomyces cerevisiae alpha-glucosidase type 1 protein conformation assessed as blue shift at 10 to 60 uM by fluorescence spectrophotometric method | Saccharomyces cerevisiae | 1 | ALA3877317 | assay format | Scientific Literature | |
20. | ALA3879451 | B | Binding affinity to Saccharomyces cerevisiae alpha-glucosidase type 1 assessed as Stern-Volmer quenching constant at 25 degC by fluorescence spectrophotometric method | Saccharomyces cerevisiae | 2 | ALA3877317 | assay format | Scientific Literature |