# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2061948 | ADME | Prodrug activation in phosphate buffer assessed as release of doxorubicin after 5 hrs by HPLC analysis in presence of human serum albumin | 2 | ALA2057162 | assay format | Scientific Literature | ||
2. | ALA2061956 | Functional | Antiproliferative activity against mouse LLC cells after 48 hrs by XTT assay | Mus musculus | 3 | ALA2057162 | cell-based format | Scientific Literature | |
3. | ALA2061957 | Functional | Antiproliferative activity against mouse LLC cells after 48 hrs by XTT assay in presence of beta glucuronidase | Mus musculus | 2 | ALA2057162 | cell-based format | Scientific Literature | |
4. | ALA2061958 | Toxicity | Toxicity in C57BL/6 mouse xenografted with mouse LLC cells assessed as mortality at 43.6 umol/kg, iv administered on day 4 and day 11 after tumor transplantation measured on day 17 | Mus musculus | 2 | ALA2057162 | organism-based format | Scientific Literature | |
5. | ALA2061960 | Toxicity | Toxicity in C57BL/6 mouse xenografted with mouse LLC cells assessed as change in body weight at 43.6 umol/kg, iv administered on day 4 and day 11 after tumor transplantation measured on day 17 | Mus musculus | 2 | ALA2057162 | organism-based format | Scientific Literature | |
6. | ALA2061963 | Functional | Antitumor activity against mouse LLC cells xenografted in C57BL/6 mouse assessed as decrease in tumor volume at 13.7 umol/kg, iv administered on day 4 and day 11 after tumor transplantation measured on day 13 | Mus musculus | 1 | ALA2057162 | organism-based format | Scientific Literature | |
7. | ALA2062081 | ADME | Elimination half life in CD-1 nu/nu mouse at 50 mg/kg, iv | Mus musculus | 1 | ALA2057162 | organism-based format | Scientific Literature | |
8. | ALA2062082 | ADME | Elimination half life in CD rat at 50 mg/kg, iv | Rattus norvegicus | 1 | ALA2057162 | organism-based format | Scientific Literature | |
9. | ALA2060784 | ADME | Elimination half life in cynomolgus monkey at 50 mg/kg, iv | Macaca fascicularis | 1 | ALA2057162 | organism-based format | Scientific Literature |