# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2061970 | B | Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma counting | Homo sapiens | 15 | ALA2057074 | single protein format | Scientific Literature | |
2. | ALA2061971 | B | Ratio of losartan IC50 to compound IC50 for AT1 receptor | Homo sapiens | 1 | ALA2057074 | single protein format | Scientific Literature | |
3. | ALA2061972 | F | Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post KCl-induction for 1 hr | Oryctolagus cuniculus | 5 | ALA2057074 | tissue-based format | Scientific Literature | |
4. | ALA2061973 | F | Antihypertensive activity in non-fasted spontaneous hypertensive rat assessed as decrease in mean arterial blood pressure at 10 mg/kg, po by tail plethysmography relative to control | Rattus norvegicus | 1 | ALA2057074 | organism-based format | Scientific Literature | |
5. | ALA2061974 | A | Toxicity against Photobacterium phosphoreum expressing T3 mutation after 15 mins by Microtox assay | Photobacterium phosphoreum | 15 | ALA2057074 | organism-based format | Scientific Literature | |
6. | ALA3736606 | B | Displacement of [125I]Sar1Ile8-Ang2 from human AT1 receptor expressed in CHO-K1 cell membranes after 180 mins | Homo sapiens | 43 | ALA3734751 | cell-based format | Scientific Literature | |
7. | ALA3736615 | B | Antagonist activity against AT1 receptor in Japanese White rabbit aortic strips assessed as reduction in angiotension-2-induced contractile response after 60 mins by Schild's plot analysis | Oryctolagus cuniculus | 15 | ALA3734751 | single protein format | Scientific Literature |