| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2060534 | B | Inhibition of SARS coronavirus nsP13 helicase activity expressed in Escherichia coli Rosetta assessed inhibition of DNA unwinding activity at 10 uM by FRET assay | SARS coronavirus | 62 | ALA2057104 | assay format | Scientific Literature | |
| 2. | ALA2060535 | B | Inhibition of HCV NS3 helicase overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of DNA unwinding activity at 10 uM by FRET assay | Hepatitis C virus | 62 | ALA2057104 | assay format | Scientific Literature | |
| 3. | ALA2060537 | B | Inhibition of HCV NS3 helicase ATP hydrolysis activity overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of inorganic phosphate release by AM/MG-based colometric analysis in the presence of M13 ssDNA | Hepatitis C virus | 62 | ALA2057104 | assay format | Scientific Literature | |
| 4. | ALA3635921 | B | Inhibition of human IDH1 R132H mutant expressed in IPTG-induced Escherichia coli BL21 cells assessed as oxidation of NADPH to NADP+ after 5 mins by spectrophotometry | Homo sapiens | 55 | ALA3632508 | cell-based format | Scientific Literature | |
| 5. | ALA3635922 | B | Inhibition of human IDH1 expressed in IPTG-induced Escherichia coli BL21 cells assessed as reduction of NADP+ to NADPH after 5 mins by spectrophotometry | Homo sapiens | 55 | ALA3632508 | cell-based format | Scientific Literature |
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