# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2060534 | B | Inhibition of SARS coronavirus nsP13 helicase activity expressed in Escherichia coli Rosetta assessed inhibition of DNA unwinding activity at 10 uM by FRET assay | SARS coronavirus | 62 | ALA2057104 | assay format | Scientific Literature | |
2. | ALA2060535 | B | Inhibition of HCV NS3 helicase overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of DNA unwinding activity at 10 uM by FRET assay | Hepatitis C virus | 62 | ALA2057104 | assay format | Scientific Literature | |
3. | ALA2060537 | B | Inhibition of HCV NS3 helicase ATP hydrolysis activity overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of inorganic phosphate release by AM/MG-based colometric analysis in the presence of M13 ssDNA | Hepatitis C virus | 62 | ALA2057104 | assay format | Scientific Literature | |
4. | ALA3387251 | F | Inhibition of histone H3 Ser10 phosphorylation in human HT-29 cells at 10 uM incubated for 1 hr by Western blotting method | Homo sapiens | 4 | ALA3352036 | cell-based format | Scientific Literature | |
5. | ALA3387252 | F | Inhibition of c-Jun protein expression in human HT-29 cells at 10 uM incubated for 1 hr by Western blotting method | Homo sapiens | 4 | ALA3352036 | cell-based format | Scientific Literature | |
6. | ALA3389099 | F | Inhibition of 14-3-3epsilon protein expression in human HT-29 cells at 10 uM incubated for 1 to 4 hrs by Western blotting method | Homo sapiens | 4 | ALA3352036 | cell-based format | Scientific Literature | |
7. | ALA3389100 | B | Inhibition of recombinant 14-3-3epsilon protein (unknown origin) expression in Escherichia coli assessed as reduction in 14-3-3epsilon and histone H3 Ser10 interaction using human HT-29 cells lysates at 1 uM incubated for 1 hr by Western blotting based GST-pull down assay | Homo sapiens | 4 | ALA3352036 | cell-based format | Scientific Literature | |
8. | ALA3389101 | B | Inhibition of Aurora A kinase phosphorylation in human HT-29 cells at 10 uM incubated for 15 to 120 mins by Western blotting method | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
9. | ALA3389102 | B | Inhibition of Aurora B kinase phosphorylation in human HT-29 cells at 10 uM incubated for 15 to 120 mins by Western blotting method | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
10. | ALA3389103 | B | Inhibition of Aurora C kinase phosphorylation in human HT-29 cells at 10 uM incubated for 15 to 120 mins by Western blotting method | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
11. | ALA3389104 | B | Inhibition of JNK1 phosphorylation in human HT-29 cells at 10 uM incubated for 15 to 120 mins by Western blotting method | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
12. | ALA3389105 | B | Inhibition of JNK2 phosphorylation in human HT-29 cells at 10 uM incubated for 15 to 120 mins by Western blotting method | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
13. | ALA3389106 | B | Inhibition of p38 phosphorylation in human HT-29 cells at 10 uM incubated for 15 to 120 mins by Western blotting method | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
14. | ALA3389107 | F | Induction of Nrf2 protein protein expression in human HT-29 cells at 10 uM incubated for 6 to 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
15. | ALA3389108 | F | Induction of HO-1 protein protein expression in human HT-29 cells at 10 uM incubated for 6 to 24 hrs by Western blotting method | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
16. | ALA3389109 | T | Toxicity against human HT-29 cells assessed as effect on cell viability at 10 uM incubated for 24 hrs by MTT assay | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
17. | ALA3389110 | F | Induction of cell cycle arrest in human HT-29 cells assessed as accumulation at subG1 phase at 10 uM incubated for 6 hrs by propidium iodide staining based FACS assay (Rvb = 0.79%) | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
18. | ALA3389111 | F | Induction of cell cycle arrest in human HT-29 cells assessed as accumulation at G0/G1 phase at 10 uM incubated for 6 hrs by propidium iodide staining based FACS assay (Rvb = 60.39%) | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
19. | ALA3389112 | F | Induction of cell cycle arrest in human HT-29 cells assessed as accumulation at S phase at 10 uM incubated for 6 hrs by propidium iodide staining based FACS assay (Rvb = 21.94%) | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature | |
20. | ALA3389113 | F | Induction of cell cycle arrest in human HT-29 cells assessed as accumulation at G2/M phase at 10 uM incubated for 6 hrs by propidium iodide staining based FACS assay (Rvb = 14.8%) | Homo sapiens | 1 | ALA3352036 | cell-based format | Scientific Literature |