#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2060736	B	Inhibition of interaction of MDM2-p53 by HTRF assay	Homo sapiens	2		protein format	Scientific Literature
2.	ALA2182639	F	Induction of p21 mRNA expression in p53 deficient human HCT116 cells after 7 hrs by RT-PCR analysis	Homo sapiens	1		cell-based format	Scientific Literature
3.	ALA2182641	F	Activity at p53 in human SJSA1 cells xenografted mouse assessed as induction of p21 mRNA expression at 300 mg/kg, qd for 4 days measured per day by RT-PCR analysis relative to control	Mus musculus	2		organism-based format	Scientific Literature
4.	ALA2182642	B	Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay	Homo sapiens	32		protein format	Scientific Literature
5.	ALA2182643	B	Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay in presence of 15% human serum	Homo sapiens	32		protein format	Scientific Literature
6.	ALA2182644	B	Activity at p53 in human SJSA1 cells assessed as induction of p21 mRNA expression after 7 hrs by qRT-PCR analysis in presence of 10% human serum	Homo sapiens	10		cell-based format	Scientific Literature
7.	ALA2182645	F	Antiproliferative activity against human SJSA1 cells after 3 days by EdU incorporation assay in presence of 10% human serum	Homo sapiens	10		cell-based format	Scientific Literature
8.	ALA2182646	F	Antiproliferative activity against human HCT116 cells expressing wild type p53 assessed as reduction in BrdU incorporation after 16 hrs by Flow cytometry	Homo sapiens	2		cell-based format	Scientific Literature
9.	ALA2182647	F	Antiproliferative activity against p53 deficient human HCT116 cells assessed as reduction in BrdU incorporation after 16 hrs by Flow cytometry	Homo sapiens	2		cell-based format	Scientific Literature
10.	ALA2182648	B	Activity at p53 in human HCT116 cells expressing wild type p53 assessed as induction of p21 mRNA expression after 7 hrs by RT-PCR analysis	Homo sapiens	1		cell-based format	Scientific Literature
11.	ALA2182649	F	Activity at p53 in human SJSA1 cells xenografted mouse assessed as induction of p21 mRNA expression at 300 mg/kg, qd for 4 days measured after 6 hrs of last dose by RT-PCR analysis relative to control	Mus musculus	1		organism-based format	Scientific Literature
12.	ALA2182650	F	Activity at p53 in human SJSA1 cells xenografted po dosed mouse assessed as induction of p21 mRNA expression administered qd for 4 days measured after 6 hrs of last dose by RT-PCR analysis	Mus musculus	1		organism-based format	Scientific Literature
13.	ALA2182651	F	Antitumor activity against human SJSA1 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 200 mg/kg, po qd for 14 days	Homo sapiens	1		organism-based format	Scientific Literature
14.	ALA2182652	B	Binding affinity to human MDM2 by SPR analysis	Homo sapiens	2		single protein format	Scientific Literature
15.	ALA2182653	B	Activation of human PXR at 2 uM relative to control	Homo sapiens	3		single protein format	Scientific Literature
16.	ALA2182654	A	Inhibition of human CYP3A4 at 3 uM	Homo sapiens	3		single protein format	Scientific Literature
17.	ALA2182655	A	Time dependent inhibition of human CYP3A4 assessed as residual activity at 10 uM after 15 mins relative to control	Homo sapiens	3		single protein format	Scientific Literature
18.	ALA2182663	F	Antitumor activity against human SJSA1 cells xenografted in po dosed athymic nude mouse assessed as tumor growth inhibition administered qd after 14 days	Homo sapiens	2		organism-based format	Scientific Literature
19.	ALA2182664	A	Intrinsic clearance in human hepatocytes assessed per million cells	Homo sapiens	2		cell-based format	Scientific Literature
20.	ALA2182665	A	Plasma clearance in rat	Rattus norvegicus	2		organism-based format	Scientific Literature