#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2060737	B	Binding affinity to human MDM2 by surface plasmon resonance binding assay	Homo sapiens	1	ALA2057187	single protein format	Scientific Literature
2.	ALA2060738	A	Oral bioavailability in mouse	Mus musculus	1	ALA2057187	organism-based format	Scientific Literature
3.	ALA2060739	A	Oral bioavailability in rat	Rattus norvegicus	1	ALA2057187	organism-based format	Scientific Literature
4.	ALA2060740	F	Antitumor activity against human SJSA1 cells xenografted in mouse assessed as tumor regression at 200 mg/kg, qd	Homo sapiens	1	ALA2057187	organism-based format	Scientific Literature
5.	ALA2182640	F	Activity at p53 in human SJSA1 cells xenografted po dosed mouse assessed as induction of p21 mRNA expression administered qd for 4 days by RT-PCR analysis relative to control	Mus musculus	1	ALA2176930	organism-based format	Scientific Literature
6.	ALA2182641	F	Activity at p53 in human SJSA1 cells xenografted mouse assessed as induction of p21 mRNA expression at 300 mg/kg, qd for 4 days measured per day by RT-PCR analysis relative to control	Mus musculus	2	ALA2176930	organism-based format	Scientific Literature
7.	ALA2182642	B	Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay	Homo sapiens	32	ALA2176930	protein format	Scientific Literature
8.	ALA2182643	B	Inhibition of human MDM2-p53 interaction after 18 hrs by HTRF assay in presence of 15% human serum	Homo sapiens	32	ALA2176930	protein format	Scientific Literature
9.	ALA2182644	B	Activity at p53 in human SJSA1 cells assessed as induction of p21 mRNA expression after 7 hrs by qRT-PCR analysis in presence of 10% human serum	Homo sapiens	10	ALA2176930	cell-based format	Scientific Literature
10.	ALA2182645	F	Antiproliferative activity against human SJSA1 cells after 3 days by EdU incorporation assay in presence of 10% human serum	Homo sapiens	10	ALA2176930	cell-based format	Scientific Literature
11.	ALA2182646	F	Antiproliferative activity against human HCT116 cells expressing wild type p53 assessed as reduction in BrdU incorporation after 16 hrs by Flow cytometry	Homo sapiens	2	ALA2176930	cell-based format	Scientific Literature
12.	ALA2182647	F	Antiproliferative activity against p53 deficient human HCT116 cells assessed as reduction in BrdU incorporation after 16 hrs by Flow cytometry	Homo sapiens	2	ALA2176930	cell-based format	Scientific Literature
13.	ALA2182652	B	Binding affinity to human MDM2 by SPR analysis	Homo sapiens	2	ALA2176930	single protein format	Scientific Literature
14.	ALA2182653	B	Activation of human PXR at 2 uM relative to control	Homo sapiens	3	ALA2176930	single protein format	Scientific Literature
15.	ALA2182654	A	Inhibition of human CYP3A4 at 3 uM	Homo sapiens	3	ALA2176930	single protein format	Scientific Literature
16.	ALA2182655	A	Time dependent inhibition of human CYP3A4 assessed as residual activity at 10 uM after 15 mins relative to control	Homo sapiens	3	ALA2176930	single protein format	Scientific Literature
17.	ALA2182656	A	Clearance in cynomolgus monkey plasma relative to hepatic blood flow	Macaca fascicularis	1	ALA2176930	organism-based format	Scientific Literature
18.	ALA2182657	A	Volume of distribution in cynomolgus monkey	Macaca fascicularis	1	ALA2176930	organism-based format	Scientific Literature
19.	ALA2182658	A	Half life in cynomolgus monkey	Macaca fascicularis	1	ALA2176930	organism-based format	Scientific Literature
20.	ALA2182659	T	Toxicity in human SJSA1 cells xenografted mouse assessed as reduction of body weight at 75 to 100 mg/kg, po bid	Mus musculus	1	ALA2176930	organism-based format	Scientific Literature