#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2061994	B	Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assay	Homo sapiens	25		cell-based format	Scientific Literature
2.	ALA2060771	B	Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysis	Homo sapiens	20		cell-based format	Scientific Literature
3.	ALA2060772	B	Inhibition of p38alpha	Homo sapiens	24		single protein format	Scientific Literature
4.	ALA2060773	P	Aqueous solubility of the compound at pH 7.4		25		small-molecule physicochemical format	Scientific Literature
5.	ALA2060774	A	Fraction unbound in human plasma	Homo sapiens	25		cell-free format	Scientific Literature
6.	ALA2060775	A	Clearance in CD-1 mouse at 3 mg/kg, iv and 10 mg/kg, po	Mus musculus	2		organism-based format	Scientific Literature
7.	ALA2060776	A	Volume of distribution at steady state in CD-1 mouse at 3 mg/kg, iv and 10 mg/kg, po	Mus musculus	2		organism-based format	Scientific Literature
8.	ALA2060777	A	AUC in CD-1 mouse at 10 mg/kg, po	Mus musculus	2		organism-based format	Scientific Literature
9.	ALA2060778	A	Half life in CD-1 mouse at 3 mg/kg, iv	Mus musculus	2		organism-based format	Scientific Literature
10.	ALA2060779	A	Oral bioavailability in CD-1 mouse at 10 mg/kg	Mus musculus	2		organism-based format	Scientific Literature
11.	ALA2060780	B	Inhibition of p38alpha at 50 uM by whole blood cell assay	Homo sapiens	1		single protein format	Scientific Literature
12.	ALA3301363	P	ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5		4,197		small-molecule physicochemical format	AstraZeneca Deposited Data
13.	ALA3301365	A	ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole human plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.	Homo sapiens	1,614		cell-free format	AstraZeneca Deposited Data
14.	ALA3301367	A	ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole dog plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.	Canis lupus familiaris	244		cell-free format	AstraZeneca Deposited Data
15.	ALA4303805	F	Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging	Homo sapiens	5,612		organism-based format	SARS-CoV-2 Screening Data 2020-21
16.	ALA4495582	F	SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate	Severe acute respiratory syndrome coronavirus 2	7,212		assay format	SARS-CoV-2 Screening Data 2020-21
17.	ALA4513082	F	Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging	Chlorocebus sabaeus	7,212		organism-based format	SARS-CoV-2 Screening Data 2020-21
18.	ALA4610865	B	Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentiation by measuring alkaline phosphatase activity incubated for 72 hrs	Mus musculus	27		cell-based format	Scientific Literature
19.	ALA4610866	P	Lipophilicity, logD of compound		27		small-molecule physicochemical format	Scientific Literature
20.	ALA4610867	P	Aqueous solubility of compound measured using solids from evaporated DMSO solution at pH 7.4		27		small-molecule physicochemical format	Scientific Literature