#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA2061994	B	Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assay	Homo sapiens	25		cell-based format	Scientific Literature
2.	ALA2060771	B	Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysis	Homo sapiens	20		cell-based format	Scientific Literature
3.	ALA2060772	B	Inhibition of p38alpha	Homo sapiens	24		single protein format	Scientific Literature
4.	ALA2060773	P	Aqueous solubility of the compound at pH 7.4		25		small-molecule physicochemical format	Scientific Literature
5.	ALA2060774	A	Fraction unbound in human plasma	Homo sapiens	25		cell-free format	Scientific Literature
6.	ALA3301363	P	ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5		4,197		small-molecule physicochemical format	AstraZeneca Deposited Data
7.	ALA3301365	A	ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole human plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound.	Homo sapiens	1,614		cell-free format	AstraZeneca Deposited Data
8.	ALA4610865	B	Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentiation by measuring alkaline phosphatase activity incubated for 72 hrs	Mus musculus	27		cell-based format	Scientific Literature
9.	ALA4610866	P	Lipophilicity, logD of compound		27		small-molecule physicochemical format	Scientific Literature
10.	ALA4610867	P	Aqueous solubility of compound measured using solids from evaporated DMSO solution at pH 7.4		27		small-molecule physicochemical format	Scientific Literature
11.	ALA4610871	A	Protein binding in human plasma assessed as unbound fraction	Homo sapiens	11		cell-free format	Scientific Literature
12.	ALA4610873	A	Drug level in mouse plasma at 40 mg/kg, po administered as single dose measured after 1 hr	Mus musculus	10		organism-based format	Scientific Literature
13.	ALA4610874	A	Drug level in mouse plasma at 40 mg/kg, po administered as single dose measured after 8 hrs	Mus musculus	11		organism-based format	Scientific Literature
14.	ALA4610875	F	Inhibition of GLI mRNA expression in mouse xenografted with human COLO205 cells at 40 mg/kg, po administered as single dose measured after 8 hrs by RT-PCR analysis relative to control	Mus musculus	11		organism-based format	Scientific Literature
15.	ALA4672711	A	Metabolic stability in human liver microsomes	Homo sapiens	22		microsome format	Scientific Literature
16.	ALA4672719	P	Lipophilicity, logD of the compound at pH 7.4 by shake flask method		22		small-molecule physicochemical format	Scientific Literature
17.	ALA4672720	P	Lipophilicity, logD of the compound at pH 7.4 by chromatography		22		small-molecule physicochemical format	Scientific Literature
18.	ALA4672721	A	Passive permeability from apical to basolateral side in human Caco-2 cells	Homo sapiens	22		cell-based format	Scientific Literature
19.	ALA4672723	P	Dissociation constant, pKa1 of compound by spectrophotometry		4		small-molecule physicochemical format	Scientific Literature
20.	ALA4672724	P	Dissociation constant, pKa2 of compound by spectrophotometry		2		small-molecule physicochemical format	Scientific Literature