| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2061994 | B | Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 2. | ALA2060771 | B | Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysis | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 3. | ALA2060772 | B | Inhibition of p38alpha | Homo sapiens | 24 | single protein format | Scientific Literature | ||
| 4. | ALA2060773 | P | Aqueous solubility of the compound at pH 7.4 | 25 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA2060774 | A | Fraction unbound in human plasma | Homo sapiens | 25 | cell-free format | Scientific Literature | ||
| 6. | ALA3301365 | A | ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with whole human plasma at 37C for >5hrs. Method described in B. Testa et al (Eds.), Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies, Wiley-VCH, Weinheim, 2006, pp.119-141. Experimental range 10% to 99.95% bound. | Homo sapiens | 1,614 | cell-free format | AstraZeneca Deposited Data |
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